Evidence map›Paper›PMID 36524033›Full record

ArticleJournal of arrhythmia2022

Antithrombotic therapy after angioplasty of pulmonary vein stenosis due to atrial fibrillation ablation: A two-center experience and review of the literature.

Thomas Fink, Julia Vogler, Riccardo Proietti, Vanessa Sciacca, Christian-Hendrik Heeger, Laura Rottner, Tilman Maurer, Andreas Metzner, Shibu Mathew, Charlotte Eitel and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of arrhythmia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 2 countries.

Thomas FinkUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Julia VoglerUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Riccardo ProiettiDepartment of Cardiac, Thoracic, and Vascular Sciences University of Padua Padua Italy.
Vanessa SciaccaUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Christian-Hendrik HeegerUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Laura RottnerDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Tilman MaurerDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Andreas MetznerDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Shibu MathewDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Charlotte EitelUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Ingo EitelUniversity Heart Centre Lübeck, Department of Cardiology, Angiology, and Intensive Care Medicine University Hospital Schleswig-Holstein Lübeck Germany.
Christian SohnsDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Makoto SanoUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Bruno ReissmannDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Andreas RilligDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Feifan OuyangDepartment of Cardiology Asklepios Klinik St. Georg Hamburg Germany.
Karl-Heinz KuckUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Roland Richard TilzUniversity Heart Centre Lübeck, Section of Electrophysiology University Hospital Schleswig-Holstein Lübeck Germany.
Asklepios Klinik St. Georg · DERuhr University Bochum · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Lübeck · DEUniversity Hospital Schleswig-Holstein · DEUniversität Hamburg · DEUniversitätsklinikum Gießen und Marburg · DEUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary vein stenosis (PVS) is a severe complication of atrial fibrillation (AF) ablation resulting in narrowing of affected pulmonary veins (PVs). Interventional treatment consists of angioplasty with or without PV stenting. The optimal postprocedural antithrombotic therapy is not known. Study aims: To investigate the impact of antithrombotic medical therapy on recurrence of PVS after PV angioplasty. Methods: A retrospective study of patients undergoing PV angioplasty with or without stent implantation in two German centers was performed. Postinterventional antithrombotic therapy consisted of either dual antiplatelet therapy (DAPT) or a combination of oral anticoagulation with single or dual antiplatelet therapy for 3-12 months after intervention. Angiographic follow-up was recommended 3, 6, and 12 months after intervention and in case of symptom recurrence. Results: Thirty patients underwent treatment of 42 PVS. After intervention, twenty-eight patients received triple therapy and 14 patients received dual therapy/DAPT; restenosis occurred in 5/22 (22.7%) patients with triple therapy and 8/14 (57.1%) patients with dual therapy/DAPT PV ( Conclusion: Triple antithrombotic therapy after PV angioplasty is associated with less frequent restenosis as compared to dual antiplatelet therapy or a combination of anticoagulation and single antiplatelet therapy. No severe bleeding events occurred in patients on triple therapy. These findings need to be confirmed in larger patient cohorts.

Indexed as

anticoagulationantiplatelet therapyatrial fibrillationpulmonary vein stenosis; restenosistriple therapy

Identifiers

PMID36524033
PMCPMC9745453
OpenAlexW4296016364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.