Evidence map›Paper›PMID 36523897›Full record

ArticleJournal of sports science & medicine2022

Changes in Muscle Shear Modulus and Urinary Titin N-Terminal Fragment after Eccentric Exercise.

Takayuki Inami, Shota Yamaguchi, Hiroyuki Ishida, Naohiko Kohtake, Akihisa Morito, Satoshi Yamada, Masatsugu Shimomasuda, Maki Haramoto, Naoya Nagata, Mitsuyoshi Murayama

Open access · bronzeAbstract read
In one paragraph

Article in Journal of sports science & medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Skeletal Muscle Damage and Inflammation.Advances in experimental medicine and biology · 2025
    Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Takayuki InamiInstitute of Physical Education, Keio University, Japan.
Shota YamaguchiInstitute of Physical Education, Keio University, Japan.
Hiroyuki IshidaSports Medicine Research Center, Keio University, Japan.
Naohiko KohtakeGraduate School of System Design Management, Keio University, Japan.
Akihisa MoritoGraduate School of System Design Management, Keio University, Japan.
Satoshi YamadaTaisho Pharmaceutical Co., Ltd. Japan.
Masatsugu ShimomasudaTaisho Pharmaceutical Co., Ltd. Japan.
Maki HaramotoTaisho Pharmaceutical Co., Ltd. Japan.
Naoya NagataInstitute of Physical Education, Keio University, Japan.
Mitsuyoshi MurayamaInstitute of Physical Education, Keio University, Japan.
Keio University · JPTaisho Pharmaceutical (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the relationship between the muscle shear modulus of the biceps brachii, urinary titin N-terminal fragment (UTF), and other damage markers after eccentric exercise. Seventeen healthy males performed five sets of ten eccentric exercises with dumbbells weighing 50% of the maximum voluntary contraction (MVC) at the elbow joint. Muscle shear modulus with range of interest set to only biceps brachii muscle measured by ultrasound shear wave elastography, UTF, MVC, range of motion (ROM), and soreness (SOR) were recorded before, immediately after, and 1, 24, 48, 72, 96, and 168 h after eccentric exercise. Each marker changed in a time course pattern, as found in previous studies. The peak shear modulus showed a moderate negative correlation with peak MVC (r = -0.531, P < 0.05) and a strong positive correlation with peak UTF (r = 0.707, P < 0.01). Our study results revealed a significant relationship between muscle strength, shear modulus measured by ultrasound SWE, and titin measured by UTF, as a non-invasive damage marker after eccentric exercise to track changes in EIMD.

Indexed as

ExerciseMuscle, SkeletalConnectinHumansMaleMuscle StrengthRange of Motion, ArticularConnectinexercise-induced muscle damagenon-invasive methodsarcomereShear wave elastographystiffness

Identifiers

PMID36523897
PMCPMC9741722
OpenAlexW4306167748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.