Evidence map›Paper›PMID 36523884›Full record

ArticleObstetric medicine2022

Primary biliary cholangitis: a rare diagnosis during pregnancy.

Inês Felizardo Lopes, Catarina R Palma Dos Reis, Maria José Alves, Filipe Calinas, Maria Augusta Borges

Open access · greenAbstract readCase Reports
In one paragraph

Article in Obstetric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Inês Felizardo LopesMedicina Interna, Maternidade Dr. Alfredo da Costa, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-0049-6865
Catarina R Palma Dos ReisServiço de Medicina Materno-fetal, Maternidade Dr. Alfredo da Costa, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
Maria José AlvesServiço de Medicina Materno-fetal, Maternidade Dr. Alfredo da Costa, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
Filipe CalinasCentro de Responsabilidade Integrado da Especialidade de Gastrenterologia, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
Maria Augusta BorgesMedicina Interna, Maternidade Dr. Alfredo da Costa, Centro Hospitalar Universitário Lisboa Central, Lisbon, Portugal.
Unidade Local de Saúde de São José · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary biliary cholangitis is an autoimmune disease that mostly affects women. It is uncommon in women of childbearing age and the diagnosis during pregnancy is rare and can be challenging. Described here is a case of primary biliary cholangitis first manifesting during pregnancy, with the onset of pruritus, jaundice, biochemical liver abnormalities and positive antimitochondrial antibodies. Although treatment with ursodeoxycholic acid was started at the time of diagnosis, there was a progressive worsening of cholestatic biochemical markers throughout pregnancy. In addition, fasting hyperglycemia with polyhydramnios was diagnosed, consistent with gestational diabetes. She had a spontaneous preterm delivery at 31 weeks of gestation, of a newborn who was admitted to the neonatal intensive care unit but who subsequently had no long-term sequelae of preterm delivery. A maternal postpartum flare occurred. Treatment with ursodeoxycholic acid was well tolerated during pregnancy and lactation.

Indexed as

cholestasisliver diseasepregnancyprimary biliary cholangitis

Identifiers

PMID36523884
PMCPMC9745597
OpenAlexW3161905922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.