Evidence map›Paper›PMID 36523790›Full record

ArticleClinical epidemiology2022

Cohort Description: Preventing an Opioid Epidemic in Norway - Focusing on Treatment of Chronic Pain (POINT) - A National Registry-Based Study.

Aleksi Hamina, Ingvild Odsbu, Petter Christian Borchgrevink, Li-Chia Chen, Thomas Clausen, Ketil Arne Espnes, Kine Gjesdal, Marte Handal, Sirpa Hartikainen, Vidar Hjellvik and 9 more

Abstract read
In one paragraph

Article in Clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Aleksi Hamina *Norwegian Centre for Addiction Research (SERAF), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0003-2417-4059
Ingvild Odsbu *Department of Mental Disorders, Division of Mental and Physical Health, the Norwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-5337-8619
Petter Christian BorchgrevinkDepartment of Pain and Complex Disorders, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
Li-Chia ChenDivision of Pharmacy and Optometry, School of Health Sciences, University of Manchester, Manchester, UK.ORCID 0000-0002-6158-6645
Thomas ClausenNorwegian Centre for Addiction Research (SERAF), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Ketil Arne EspnesDepartment of Clinical Pharmacology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID 0000-0002-3566-3328
Kine GjesdalFaculty of Health Sciences, University of Stavanger, Stavanger, Norway.ORCID 0000-0002-0812-0168
Marte HandalNorwegian Centre for Addiction Research (SERAF), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Sirpa HartikainenSchool of Pharmacy, University of Eastern Finland, Kuopio, Finland.
Vidar HjellvikDepartment of Chronic Diseases, Division of Mental and Physical Health, the Norwegian Institute of Public Health, Oslo, Norway.
Marianne Therese Smogeli HolterDepartment of Psychology, Faculty of Social Sciences, University of Oslo, Oslo, Norway.
Trond HøibøResearch Unit for General Practice, NORCE Norwegian Research Centre, Bergen, Norway.
Geana Paula KuritaDepartment of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Harald Christian LangaasRegional Medicines Information and Pharmacovigilance Centre (RELIS), Department of Clinical Pharmacology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID 0000-0002-6787-5552
Torgeir Gilje LidFaculty of Health Sciences, University of Stavanger, Stavanger, Norway.ORCID 0000-0003-0088-411X
Torunn Hatlen NøstDepartment of Pain and Complex Disorders, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID 0000-0003-1149-7238
Per SjøgrenDepartment of Oncology, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark.
Svetlana SkurtveitNorwegian Centre for Addiction Research (SERAF), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
POINT study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The POINT project aims to provide evidence to optimise chronic pain management, prevent adverse consequences of opioids, and improve chronic pain patients' pain relief, functional capacity, and quality of life. We describe the outline of the project and its work packages. More specifically, we describe a cohort of persons with chronic pain and a cohort of long-term opioid users identified from a national registry linkage. Data Sources: The project utilises data from nationwide healthcare and population registers in Norway. Using the Norwegian Prescription Database, we identified a cohort of persons who have been dispensed drugs reimbursed for chronic pain and a cohort of persons who used opioids long term from 2010 to 2019. Data from the Norwegian Registry for Primary Health Care and the Norwegian Patient Registry (2008-2019), Cancer Registry (1990-2018) Cause of Death Registry (2010-2019) and demographic and socioeconomic registers from Statistics Norway (2010-2019) were linked to the cohorts. Study Population: There were 568,869 participants with chronic pain. Sixty-three percent of the cohort was women, and the mean age was 57.1 years. There were 336,712 long-term opioid users (58.6% women; 60.9 years). In chronic pain and long-term opioid user cohorts, the most frequent musculoskeletal diagnosis was back pain diagnosed in primary care (27.6% and 30.7%). Psychiatric diagnoses were also common. Main Variables: Upcoming studies will utilise psychiatric and somatic diagnoses from the patient registers, drug use from the prescription register, causes of death, demographics, and socioeconomic status (eg, education, income, workability, immigrant status) as exposures or outcomes. Conclusion and Future Plans: The two cohorts have numerous pain-related diagnoses, especially in the musculoskeletal system, and noticeably frequent somatic and psychiatric morbidity. The POINT project also includes later work packages that explore prescriber and patient perspectives around safe and effective treatment of chronic pain.

Indexed as

chronic painhealthcare registersopioids

Identifiers

PMID36523790
PMCPMC9744863

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.