SynthesisFrontiers in medicine2022
Anxiety, depression, and quality of life in children and adults with alopecia areata: A systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- S3 guideline diagnostics and therapy of alopecia areata - Part 1: Diagnostics and epidemiology.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026Guideline
- A systematic review and meta-synthesis of qualitative studies of alopecia: Managing identity and appearance changes.British journal of health psychology · 2026Pooled it
- Pooled it
- Psychosocial impact of alopecia areata in paediatric and adolescent populations: A systematic review.Journal of paediatrics and child health · 2024Pooled it
- Psychiatric Comorbidity in Hidradenitis Suppurativa-A Large-Scale Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Developing recommendations for promoting wellbeing in individuals with alopecia areata: a modified Delphi study.BMJ open · 2026Article
- Topical Metformin Compared with Clobetasol Propionate for Alopecia Areata: Clinical Outcomes from a Comparative Study.Dermatology practical & conceptual · 2026Article
- JAK Inhibitors for Alopecia Areata: Approved Therapies, Efficacy, and Unanswered Questions.Drug design, development and therapy · 2026Review
- Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions.ADMET & DMPK · 2026Review
- Technological Advances in Anti-hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation.Aesthetic plastic surgery · 2025Review
- Responsiveness of the Dermatology Life Quality Index and the Colombian Validated Version of the Skindex-29 in Scarring and Non-Scarring Alopecia.Skin appendage disorders · 2025Article
- The experience of living with vitiligo in Nigeria: A participatory Interpretative Phenomenological Analysis.Journal of health psychology · 2025Article
- Emotional burden and current management practices in pediatric alopecia areata: An online survey among physicians.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025Article
- Switching JAK inhibitors: evaluating baricitinib's effectiveness in alopecia areata after tofacitinib failure.Archives of dermatological research · 2025Article
- Survey on Alopecia Areata Patients' Reported Factors that Determine Severity of Alopecia Areata: A Nationwide Multicenter Study.Annals of dermatology · 2024Article
- Association Between Scalp Microbiota Imbalance, Disease Severity, and Systemic Inflammatory Markers in Alopecia Areata.Dermatology and therapy · 2024Article
- Psychodermatology in Hungary: Awareness and practice patterns of dermatologists.Skin health and disease · 2024Article
- Korean Consensus Criteria for the Severity Classification of Alopecia Areata.Annals of dermatology · 2024Article
- Depressive Disorder and Dermatological Autoimmune Diseases.Journal of clinical medicine · 2024Review
- Establishing the financial burden of alopecia areata and its predictors.Skin health and disease · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Alopecia areata (AA) is a non-scarring hair loss condition, subclassified into AA, alopecia universalis, and alopecia totalis. There are indications that people with AA experience adverse psychosocial outcomes, but previous studies have not included a thorough meta-analysis and did not compare people with AA to people with other dermatological diagnoses. Therefore, the aim of this systematic review and meta-analysis was to update and expand previous systematic reviews, as well as describing and quantifying levels of anxiety, depression, and quality of life (QoL) in children and adults with AA. Methods: A search was conducted, yielding 1,249 unique records of which 93 were included. Results: Review results showed that people with AA have higher chances of being diagnosed with anxiety and/or depression and experience impaired QoL. Their psychosocial outcomes are often similar to other people with a dermatological condition. Meta-analytic results showed significantly more symptoms of anxiety and depression in adults with AA compared to healthy controls. Results also showed a moderate impact on QoL. These results further highlight that AA, despite causing little physical impairments, can have a significant amount on patients' well-being. Discussion: Future studies should examine the influence of disease severity, disease duration, remission and relapse, and medication use to shed light on at-risk groups in need of referral to psychological care. Systematic review registration: [https://www.crd.york.ac.uk/prospero/], identifier [CRD42022323174].
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.