Evidence map›Paper›PMID 36523647›Full record

ArticleRadiology. Artificial intelligence2022

Exploring the Acceleration Limits of Deep Learning Variational Network-based Two-dimensional Brain MRI.

Alireza Radmanesh, Matthew J Muckley, Tullie Murrell, Emma Lindsey, Anuroop Sriram, Florian Knoll, Daniel K Sodickson, Yvonne W Lui

Open access · greenAbstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Alireza Radmanesh *Department of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).
Matthew J Muckley *Department of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0002-6525-8817
Tullie MurrellDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0001-5592-8218
Emma LindseyDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0003-2452-1014
Anuroop SriramDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0001-6295-7535
Florian KnollDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0001-5357-8656
Daniel K SodicksonDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID 0000-0002-2436-4664
Yvonne W LuiDepartment of Radiology, NYU School of Medicine-NYU Langone Health, New York, NY (A.R., E.L., D.K.S., Y.W.L.); Meta AI, Facebook, 770 Broadway, 2nd Floor, New York, NY 10003 (M.J.M.); Stealth, New York, NY (T.M.); Department of Artificial Intelligence Research, Meta AI, Facebook, Menlo Park, Calif (A.S.); and Department Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany (F.K.).ORCID https://orcid.org/0000-0002-9984-9164
Meta (Israel) · ILFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Purpose: To explore the limits of deep learning-based brain MRI reconstruction and identify useful acceleration ranges for general-purpose imaging and potential screening. Materials and Methods: In this retrospective study conducted from 2019 through 2021, a model was trained for reconstruction on 5847 brain MR images. Performance was evaluated across a wide range of accelerations (up to 100-fold along a single phase-encoded direction for two-dimensional [2D] sections) on the fastMRI test set collected at New York University, consisting of 558 image volumes. In a sample of 69 volumes, reconstructions were classified by radiologists for identification of two clinical thresholds: Results: Radiologists rated 100% of 69 volumes as having sufficient image quality for general-purpose imaging at up to 4× acceleration and 65 of 69 volumes (94%) as having sufficient image quality for screening at up to 14× acceleration. The Monte Carlo procedure estimated ground truth peak signal-to-noise ratio and mean squared error with coefficients of determination greater than 0.5 at 2× to 20× acceleration levels. Out-of-distribution experiments demonstrated the model's ability to produce images substantially distinct from the training set, even at 100× acceleration. Conclusion: For 2D brain images using deep learning-based reconstruction, maximum acceleration for potential screening was three to four times higher than that for diagnostic general-purpose imaging.

Indexed as

Deep LearningHigh AccelerationMRI ReconstructionOut of DistributionScreening

Identifiers

PMID36523647
PMCPMC9745443
OpenAlexW4307921997

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.