ArticleFrontiers in plant science2022
Widely targeted metabolomics analysis reveals the mechanism of quality improvement of flue-cured tobacco.
Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 22 citations in OpenAlex.
- Analysis of the effect of variable frequency fan on tobacco metabolites during curing via untargeted metabolomics.BMC plant biology · 2026Article
- New insights into tobacco leaf browning during flue-curing: antioxidant capacity-ROS imbalance is closely associated with browning development.BMC plant biology · 2026Article
- Responses and adaptations of plants to abiotic stress: transcriptional regulation of secondary metabolic pathways, metabolomics, and nanobiological approaches.Frontiers in genetics · 2026Review
- Enhancing tobacco quality through microbial-enzymatic processing: mechanisms, applications, and future perspectives.Frontiers in bioengineering and biotechnology · 2026Review
- Harvest maturity is associated with carbon reallocation and fresh-to-flue-cured metabolic changes inFrontiers in plant science · 2026Article
- Differential chlorophyll and carotenoid degradation underpin poor curing colour of low-quality flue-cured tobacco leaves.Frontiers in plant science · 2026Article
- Regional metabolomic profiling reveals lipid metabolic signatures associated with oil content in flue-cured tobacco.Frontiers in plant science · 2026Article
- Metabolic response of tobacco leaves to dry-bulb temperature variation during flue curing: a nontargeted metabolomic approach.Frontiers in plant science · 2026Article
- Metabolomics reveals signature metabolites associated with high-oiliness flue-cured tobacco (Frontiers in plant science · 2026Article
- Effects of moisture-preserving yellowing process optimization on cell physiology and post-curing chemical composition.BMC plant biology · 2025Article
- Integrative transcriptomics and metabolomics analyses reveals Maillard reaction and antioxidant capacity-mediated leaf Browning during the flue-curing process in Nicotiana tabacum L.BMC plant biology · 2025Article
- Transcriptomic and metabolomic analysis of carotenoid metabolism and accumulation of carotenoid-derived products in tobacco leaves before and after curing.Frontiers in plant science · 2025Article
- Metabolomic analysis of Yunnan cigar tobacco leaves: impact of geography and climate on flavor characteristics and machine learning-based origin traceability.Frontiers in plant science · 2025Article
- The effect of flue-curing and redrying on the diversity of fungal communities in tobacco leaves.BMC microbiology · 2024Article
- A near-complete assembly of the Houttuynia cordata genome provides insights into the regulatory mechanism of flavonoid biosynthesis in Yuxingcao.Plant communications · 2024Article
- Widely targeted metabolomic analysis reveals effects of yellowing process time on the flavor of vine tea (Food chemistry: X · 2024Article
- Unraveling crop enzymatic browning through integrated omics.Frontiers in plant science · 2024Review
- Degradation and mechanism analysis of protein macromolecules by functional bacteria in tobacco leaves.Frontiers in microbiology · 2024Article
- LC-MS/MS-based metabolic profiling: unraveling the impact of varying degrees of curing on metabolite transformations in tobacco.Frontiers in plant science · 2024Article
- Widely Targeted Volatilomics and Metabolomics Analysis Reveal the Metabolic Composition and Diversity of Zingiberaceae Plants.Metabolites · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flue-curing of top leaves with stems is a widely applied curing technology. Owing to the presence of stems, the quality of flue-cured leaves was significantly improved. However, the contribution of stems to flue-cured leaves is still unknown. In this study, the differences in physicochemical properties and metabolomics data between separated leaves (stem(-)) and leaves with stems (stem(+)) were investigated. The metabolic profiling of stem(+) was significantly different from that of stem(-), with phytohormone indole-3-acetic acid (IAA) being one of the most differential metabolites. The presence of stems reduced the rate of water loss in leaves, which led to less ROS accumulation, higher antioxidant enzyme activities and a lower level of membrane lipid peroxidation in stem(+) than in stem(-). The presence of stems also helped maintain the cellular membrane integrity of leaf cells by preventing the accumulation of IAA in leaf cells. Better cellular membrane integrity during flue-curing means a lower risk of leaf browning. In addition, stem(+) had a lower starch content than stem(-) because of a higher level of amylase activity. In summary, these results indicated that the presence of stems caused metabolism changes in leaves, prevented flue-cured leaves from browning and enhanced starch degradation in leaves during flue-curing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.