Evidence map›Paper›PMID 36523508›Full record

ArticleFrontiers in cell and developmental biology2022

An imaging-based RNA interference screen for modulators of the Rab6-mediated Golgi-to-ER pathway in mammalian cells.

Linda F Heffernan, Pia M Suckrau, Teerna Banerjee, Margaritha M Mysior, Jeremy C Simpson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Linda F HeffernanCell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.
Pia M SuckrauCell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.
Teerna BanerjeeCell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.
Margaritha M MysiorCell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.
Jeremy C SimpsonCell Screening Laboratory, UCD School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.
University College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammalian cells, membrane traffic pathways play a critical role in connecting the various compartments of the endomembrane system. Each of these pathways is highly regulated, requiring specific machinery to ensure their fidelity. In the early secretory pathway, transport between the endoplasmic reticulum (ER) and Golgi apparatus is largely regulated

Indexed as

membrane traffickingRab6-dependent retrograde pathwayRab GTPasesSCFD1/SLY1SMSNARE

Identifiers

PMID36523508
PMCPMC9745180
OpenAlexW4310204543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.