ArticleFrontiers in neuroscience2022
Modulation of cerebral cortex activity by acupuncture in patients with prolonged disorder of consciousness: An fNIRS study.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- A systematic review and coordinate-based meta-analysis of fMRI studies on acupuncture at LR 3.Frontiers in neuroscience · 2024Pooled it
- Immediate large-scale cortical network changes following acupuncture in patients with disorders of consciousness: a resting-state fNIRS study.Frontiers in neuroscience · 2026Article
- Acute prefrontal hemodynamic responses to Xingnao Kaiqiao acupuncture in healthy participants and patients with prolonged disorders of consciousness.Frontiers in neurology · 2026Article
- Acupotomy at spinal acupoints for primary insomnia: an exploration of therapeutic effectiveness.American journal of translational research · 2026Article
- Functional near-infrared spectroscopy for the assessment and treatment of patients with disorders of consciousness.Frontiers in neurology · 2025Review
- Efficacy of repetitive transcranial magnetic stimulation for consciousness recovery in children with disorders of consciousness following traumatic brain injury.Frontiers in neurology · 2025Article
- Analysis of the application of functional near-infrared spectroscopy in acupuncture research: a review.Frontiers in neurology · 2025Review
- Aberrant amplitude of low-frequency fluctuation and functional connectivity in children with different subtypes of ADHD: a resting-state fNIRS study.BMC psychiatry · 2024Article
- Real-Time Hemodynamic Changes in the Prefrontal and Bilateral Temporal Cortices During Intradermal Acupuncture for Major Depressive Disorder: A Prospective, Single-Center, Controlled Trial Protocol.Neuropsychiatric disease and treatment · 2023Article
- Applications of functional near-infrared spectroscopy in non-drug therapy of traditional Chinese medicine: a review.Frontiers in neuroscience · 2023Review
- Six rehabilitation methods with acupuncture on consciousness in patients with traumatic brain injury: protocol for a network meta-analysis.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objective: Acupuncture is a promising non-pharmacological therapy for patients with prolonged disorder of consciousness (PDOC); however, its underlying mechanism remains uncertain. This study aimed to reveal the modulatory effects of acupuncture on the cerebral cortex activity among patients with PDOC. Materials and methods: Twenty-eight PDOC patients were randomly assigned to the treatment ( Results: Compared to the control group, a single session of acupuncture significantly tended to enhance resting-state functional connectivity (rsFC) in DLPFC-M1, DLPFC-M1, and S1-S1. And the activation level of the DLPFC (both sides) in the acupuncture group is significantly higher than those in sham acupuncture group. However, no significant correlation was found between the consciousness level and activation response/functional connectivity. Conclusion: One session of acupuncture has a significant modulation of rsFC and activation in the DLPFC, M1, and S1 with PDOC patients. Acupuncture-evoked effect may have some functional significance in PDOC patients. This is an important step toward exploring the acupuncture effects on PDOC patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.