Evidence map›Paper›PMID 36523235›Full record

ArticleBMJ open2022

Efficacy of perioperative intravenous lidocaine infusion on postoperative pulmonary complications in patients undergoing video-assisted thoracoscopic lung resection surgery: protocol for a randomised controlled trial.

Fei Wang, Yanxia He, Miyi Zhou, Qingyong Luo, Zuojia Zeng, Li Liu, Si Zeng, Qian Lei

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fei Wang *Department of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Yanxia He *Department of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Miyi ZhouDepartment of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Qingyong LuoDepartment of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Zuojia ZengDepartment of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Li LiuDepartment of Anesthesiology, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Si ZengDepartment of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China 63637936@qq.com.ORCID 0000-0002-9777-0946
Qian LeiDepartment of Anesthesiology, Sichuan Academy of Medical Sciences and Sichuan People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
University of Electronic Science and Technology of China · CNChengdu University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostoperative pulmonary complications (PPCs) are the most common complications following thoracoscopic surgery, resulting in increased hospital costs and perioperative mortality. Studies have shown that intravenous lidocaine infusion can exert its anti-inflammatory properties by reducing the release of proinflammatory cytokines. This study is designed to investigate whether intraoperative intravenous lidocaine infusion can reduce the incidence of PPCs in adult patients undergoing video-assisted thoracoscopic lung resection surgery. METHODS AND ANALYSIS: This single-centre, double-blinded study will enrol 366 patients scheduled for video-assisted thoracoscopic lung resection surgery. Patients will be randomly assigned to the lidocaine or placebo infusion group in a 1: 1 ratio. The lidocaine group will receive lidocaine intravenously during the intraoperative period, while the placebo group will be administered normal saline at an equal volume, infusion rate and timing. The primary outcome is the incidence of PPCs within 7 days following surgery. The secondary outcomes are quality of postoperative recovery 40 scores; length of hospital stay (determined by the number of days from admission to discharge); incidence of moderate to severe pain within 24 and 48 hours at rest and when coughing; incidence of additional rescue analgesics use and incidence of adverse events. ETHICS AND DISSEMINATION: The study was reviewed and approved by the Ethics Committee of Sichuan Provincial People's Hospital (approval no. 20222241). Written informed consent will be obtained from all patients before randomisation. The results of this trial will be disseminated in a peer-reviewed journal. TRIAL REGISTRATION NUMBER: ChiCTR2200061979.

Indexed as

Postoperative PainThoracic Surgery, Video-AssistedAdultAnesthetics, LocalDouble-Blind MethodHumansInfusions, IntravenousLidocaineLungPostoperative ComplicationsRandomized Controlled Trials as TopicAnesthetics, LocalLidocaineadult anaesthesiacardiothoracic surgerysurgery

Identifiers

PMID36523235
PMCPMC9748955
OpenAlexW4311223599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.