Evidence map›Paper›PMID 36523225›Full record

ArticleBMJ open2022

External validation of the risk prediction model for early diabetic kidney disease in Taiwan population: a retrospective cohort study.

Zhenzhen Sun, Kun Wang, Joshua D Miller, Xiaodan Yuan, Yau-Jiunn Lee, Qingqing Lou

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhenzhen SunHainan Clinical Research Center for metabolic disease, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Kun WangNursing College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Joshua D MillerDepartment of Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, New York, USA.
Xiaodan YuanDepartment of Public Health, Affiliated Hospital of Integrated Traditional Chinese and Western, Nanjing, China.
Yau-Jiunn LeeDepartment of Endocrinology, Lee's Clinic, Taiwan, China.
Qingqing LouHainan Clinical Research Center for metabolic disease, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China 2444890144@qq.com.ORCID 0000-0002-4743-0900

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to independently and externally validate the Risk Prediction Model for Diabetic Kidney Disease (RPM-DKD) in patients with type 2 diabetes mellitus (T2DM).

designThis is a retrospective cohort study.

settingOutpatient clinics at Lee's United Clinics, Taiwan, China.

participantsA total of 2504 patients (average age 55.44 years, SD, 7.49 years) and 4455 patients (average age 57.88 years, SD, 8.80 years) were included for analysis in the DKD prediction and progression prediction cohorts, respectively. EXPOSURE: The predicted risk for DKD and DKD progression for each patient were all calculated using the RPM-DKD. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome measure was overall incidence of DKD. Secondary outcomes included DKD progression. The discrimination, calibration and precision of the RPM-DKD score were assessed.

resultsThe DKD prediction cohort and progression prediction cohort consisted of patients with 2504 and 4455 T2DM, respectively. The RPM-DKD examined in this study showed moderately discriminative ability with area under the curve ranged from 0.636 to 0.681 for the occurrence of DKD and 0.620 to 0.654 for the progression of DKD. The Hosmer-Lemeshow χ

conclusionsOn external validation, the RPM-DKD cannot accurately predict the risk of DKD occurrence and progression in patients with T2DM.

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesHumansMiddle AgedRetrospective StudiesRisk FactorsTaiwanDIABETES & ENDOCRINOLOGYDiabetic nephropathy & vascular diseaseGeneral diabetes

Identifiers

PMID36523225
PMCPMC9748925

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.