Evidence map›Paper›PMID 36522814›Full record

ArticleArchives of biochemistry and biophysics2023

A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway.

Emily B Lancaster, William H Johnson, Jake A LeVieux, Haley A Hardtke, Yan Jessie Zhang, Christian P Whitman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emily B LancasterDivision of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas, Austin, TX, 78712, USA.
William H JohnsonDivision of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas, Austin, TX, 78712, USA.
Jake A LeVieuxDepartment of Molecular Biosciences, and University of Texas, Austin, TX, 78712, USA.
Haley A HardtkeDepartment of Molecular Biosciences, and University of Texas, Austin, TX, 78712, USA.
Yan Jessie ZhangDepartment of Molecular Biosciences, and University of Texas, Austin, TX, 78712, USA; Institute for Cellular and Molecular Biology, University of Texas, Austin, TX, 78712, USA.
Christian P WhitmanDivision of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas, Austin, TX, 78712, USA; Institute for Cellular and Molecular Biology, University of Texas, Austin, TX, 78712, USA. Electronic address: whitman@austin.utexas.edu.

Funding

Structure-Function Relationships in the Tautomerase SuperfamilyR01GM129331 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI WHITMAN, CHRISTIAN P. · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM129331
6 · The paper itself

Abstract

NahE is a hydratase-aldolase that converts o-substituted trans-benzylidenepyruvates (H, OH, or CO

Indexed as

Fructose-Bisphosphate AldolaseSchiff BasesAldehyde-LyasesAldehydesBinding SitesCatalysisHydrolasesKineticsLysineMutagensNaphthalenesSubstrate SpecificityAldehyde-LyasesAldehydesFructose-Bisphosphate AldolaseHydrolasesLysineMutagensNaphthalenessalicylaldehydeSchiff BasesActive-site mutantsEnzyme kineticsHydratase-aldolaseNaphthalene catabolic pathwaySchiff base

Identifiers

PMID36522814
PMCPMC9762252

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.