Evidence map›Paper›PMID 36522586›Full record

ArticlePflugers Archiv : European journal of physiology2023

Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and K

Klaus-Daniel Cortés Franco, Ilka C Brakmann, Maria Feoktistova, Diana Panayotova-Dimitrova, Stefan Gründer, Yuemin Tian

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Brain Tumor Stem Cells: New Perspectives.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  4. Review
  5. pH-regulated single cell migration.Pflugers Archiv : European journal of physiology · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Klaus-Daniel Cortés FrancoInstitute of Physiology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.
Ilka C BrakmannInstitute of Physiology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.
Maria FeoktistovaDepartment of Dermatology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.
Diana Panayotova-DimitrovaDepartment of Dermatology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.
Stefan GründerInstitute of Physiology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany. sgruender@ukaachen.de.
Yuemin TianInstitute of Physiology, RWTH Aachen University, Pauwelsstraße 30, D-52074, Aachen, Germany.
RWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The microenvironment of proliferative and aggressive tumours, such as the brain tumour glioblastoma multiforme (GBM), is often acidic, hypoxic, and nutrient deficient. Acid-sensing ion channels (ASICs) are proton-sensitive Na

Indexed as

GlioblastomaAcid Sensing Ion ChannelsHumansHydrogen-Ion ConcentrationIntermediate-Conductance Calcium-Activated Potassium ChannelsNeoplastic Stem CellsPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesTumor MicroenvironmentAcid Sensing Ion ChannelsIntermediate-Conductance Calcium-Activated Potassium ChannelsPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesAcid sensing ion channelExtracellular acidityGlioblastoma multiformeTumour microenvironmentTumour spheroids

Identifiers

PMID36522586
PMCPMC9908655
OpenAlexW4311599763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.