Evidence map›Paper›PMID 36522555›Full record

ArticleHeart and vessels2023

Prostaglandin E

Takayasu Kanno, Naoki Nakagawa, Tatsuya Aonuma, Jun-Ichi Kawabe, Koh-Ichi Yuhki, Naofumi Takehara, Naoyuki Hasebe, Fumitaka Ushikubi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heart and vessels, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Prostanoids in Cardiac and Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Takayasu KannoDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Naoki NakagawaDivision of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Japan. naka-nao@asahikawa-med.ac.jp.ORCID http://orcid.org/0000-0002-5398-3667
Tatsuya AonumaDivision of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Japan.
Jun-Ichi KawabeDepartment of Cardiovascular Regeneration and Innovation, Asahikawa Medical University, Asahikawa, Japan.
Koh-Ichi YuhkiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Naofumi TakeharaDivision of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Japan.
Naoyuki HasebeDivision of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, 2-1-1-1 Midorigaoka-Higashi, Asahikawa, Japan.
Fumitaka UshikubiDepartment of Pharmacology, Asahikawa Medical University, Asahikawa, Japan.
Asahikawa Medical University · JPAsahikawa Medical College Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic preconditioning (IPC) describes a phenomenon wherein brief ischemia of the heart induces a potent cardioprotective mechanism against succeeding ischemic insult. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostanoid biosynthesis, is upregulated in the ischemic heart and contributes to IPC. Prostaglandin E

Indexed as

Ischemic Preconditioning, MyocardialMyocardial InfarctionMyocardial Reperfusion InjuryAnimalsCyclooxygenase 2MiceProstaglandinsProto-Oncogene Proteins c-aktCyclooxygenase 2ProstaglandinsProto-Oncogene Proteins c-aktAkt pathwayEP4Ischemia–reperfusion injuryIschemic preconditioningProstaglandin E2

Identifiers

PMID36522555
PMCPMC9986202
OpenAlexW4311671291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.