ArticleScientific reports2022
COVID-19 infection and vaccine have no impact on in-vitro fertilization (IVF) outcome.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of COVID-19 Vaccination onInternational journal of fertility & sterility · 2024Pooled it
- Impact of SARS-CoV-2 infection on clinical outcomes ofFrontiers in endocrinology · 2023Pooled it
- The influence of SARS-CoV-2 vaccination on in vitro fertilization outcomes.Human vaccines & immunotherapeutics · 2025Article
- Pregnancy and obstetric outcomes of frozen-thawed embryo transfer with embryos generated from COVID‑19 infection during controlled ovarian stimulation: a retrospective study.Journal of assisted reproduction and genetics · 2025Article
- Effects of SARS-CoV-2 infection during IVF treatment on embryo morphokinetics and pregnancy outcomes after fresh transfer: a prospective cohort study.Reproductive biology and endocrinology : RB&E · 2025Article
- Prior COVID-19 infection increases degenerated oocytes but does not affect IVF outcomes: a prospective cohort study.Frontiers in endocrinology · 2025Observational
- Effects of COVID-19 convalescence on pregnancy outcomes in frozen-thawed embryo transfer: A retrospective cohort study.PloS one · 2025Article
- Impact of COVID-19 infection on laboratory and clinical outcomes of ovarian stimulation using antagonist protocol.Frontiers in medicine · 2025Article
- Distance and similarity measures on belief and plausibility under q-rung orthopair fuzzy sets with applications.Scientific reports · 2024Article
- The impact of SARS-CoV-2 mRNA vaccine on intracytoplasmic sperm injection outcomes at a fertility center in Iraq: A prospective cohort study.Health science reports · 2024Article
- The type of COVID-19 vaccination does not affect reproductive function and pregnancy outcomes in infertile couples.Frontiers in endocrinology · 2024Article
- Article
- COVID-19 Vaccines and Assisted Reproductive Techniques: A Systematic Review.Journal of personalized medicine · 2023Review
- Effects of COVID-19 Infection and Vaccination on the Female Reproductive System: A Narrative ReviewBalkan medical journal · 2023Review
- Impact of COVID-19 convalescence on pregnancy outcomes in patients undergoing IVF/ICSI during fresh ART cycles: a retrospective cohort study.Frontiers in endocrinology · 2023Article
- Effect of prior female SARS-CoV-2 infection on IVF outcomes: a prospective cohort study.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the effect of COVID-19 infection or vaccine on IVF outcome. This is a multicenter retrospective study. Data were collected from all patients treated in the ART units between September and November 2021 after the vaccination of the general population began. Medical records of all patients who had IVF/intracytoplasmic sperm injection (ICSI) were retrospectively reviewed. Patients were categorized into four groups: previously infected by COVID-19, vaccinated by COVID vaccine, previously infected and vaccinated, or neither infected nor vaccinated. Total number of participants 151 (vaccinated only 66, infected only 18, vaccinated and previously infected 34, and control 33. Outcomes (ET on day of trigger, number of oocytes retrieved, quality of oocytes, number of fertilized oocytes, number and quality of embryos, number of embryos transferred, number of embryos frozen, implantation rate and clinical pregnancy rate) were compared between these four groups. Moreover, we compared the outcome before and post infection, as well as before and post vaccine in a group of patients. No evidence was found to suggest that COVID-19 disease or SARS-CoV-2 Vaccine adversely affects Clinical pregnancy rates (positive fetal heartbeat) (OR 0.9, CI 0.5-1.9, OR 1.8, CI 0.9-3.6, respectively) and the following parameters: fertilization rate, implantation rate, positive bHcg) (OR 0.9, CI 0.5-1.8, OR 1.5, CI 0.7-2.9, respectively). Although a limitation of our study is the small comparison groups, and the wide confidence intervals in the Odds Ratio estimates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.