Evidence map›Paper›PMID 36521961›Full record

ArticleAJNR. American journal of neuroradiology2023

Association between Infarct Location and Hemorrhagic Transformation of Acute Ischemic Stroke following Successful Recanalization after Mechanical Thrombectomy.

H Ni, G-D Lu, Y Hang, Z-Y Jia, Y-Z Cao, H-B Shi, S Liu, L-B Zhao

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  5. CT hyperdensities after recanalization for anterior circulation large vessels occlusion: a predictor for malignant brain edema after ischemic stroke?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

H NiFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-8537-3751
G-D LuFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0001-8175-8435
Y HangFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0003-1623-2124
Z-Y JiaFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-9377-3242
Y-Z CaoFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-2451-2815
H-B ShiFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0003-1293-5789
S LiuFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID 0000-0002-9520-0202
L-B ZhaoFrom the Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China linborzhao@163.com.ORCID 0000-0001-5209-1512
Jiangsu Province Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe association between infarct location and hemorrhagic transformation of acute ischemic stroke after mechanical thrombectomy is not understood. We aimed to evaluate the association between CTP-based ischemic core variables at admission and hemorrhagic transformation after a successful thrombectomy. MATERIALS AND

methodsWe retrospectively analyzed patients who underwent endovascular thrombectomy for acute anterior circulation large-vessel occlusion between October 2019 and June 2021. We enrolled 146 patients with visible ischemic core on pretreatment CTP who had successful reperfusion. The ischemic core infarct territories were classified into the cortical and subcortical areas and then qualitatively and quantitatively analyzed by CTP. Logistic regression and receiver operating characteristic curve analyses were performed to determine the association between ischemic core variables and hemorrhagic transformation.

resultsOf the 146 patients analyzed, 72 (49.3%) had hemorrhagic transformation and 23 (15.8%) had symptomatic intracerebral hemorrhage. Multivariate analysis showed that subcortical infarcts were independently associated with hemorrhagic transformation (OR, 8.06; 95% CI, 2.31-28.10;

conclusionsSubcortical infarcts seen on CTP at admission are associated with hemorrhagic transformation in patients after successful thrombectomy, and subcortical infarct volume may influence the risk of symptomatic intracerebral hemorrhage.

Indexed as

Brain IschemiaIschemic StrokeStrokeCerebral HemorrhageCerebral InfarctionHumansRetrospective StudiesThrombectomyTomography, X-Ray ComputedTreatment Outcome

Identifiers

PMID36521961
PMCPMC9835909
OpenAlexW4311662135

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.