Evidence map›Paper›PMID 36521845›Full record

ReviewFEMS microbiology reviews2023

Origins of symbiosis: shared mechanisms underlying microbial pathogenesis, commensalism and mutualism of plants and animals.

Christina L Wiesmann, Nicole R Wang, Yue Zhang, Zhexian Liu, Cara H Haney

Open access · greenAbstract readReview
In one paragraph

Review in FEMS microbiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. InferiorMicrobial genomics · 2024
    Pooled it
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  16. Microbiome and Communication Disorders: A Tutorial for Clinicians.Journal of speech, language, and hearing research : JSLHR · 2025
    Review
  17. Review
  18. Proteome-wide bioinformatic annotation and functional validation of the monotopic phosphoglycosyl transferase superfamily.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christina L WiesmannDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Nicole R WangDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Yue ZhangDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Zhexian LiuDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Cara H HaneyDepartment of Microbiology and Immunology, The University of British Columbia, Vancouver, BC V6T 1Z3, Canada.ORCID 0000-0002-6099-6677
University of British Columbia · CA

Funding

CIHR PJT-169051NSERC
6 · The paper itself

Abstract

Regardless of the outcome of symbiosis, whether it is pathogenic, mutualistic or commensal, bacteria must first colonize their hosts. Intriguingly, closely related bacteria that colonize diverse hosts with diverse outcomes of symbiosis have conserved host-association and virulence factors. This review describes commonalities in the process of becoming host associated amongst bacteria with diverse lifestyles. Whether a pathogen, commensal or mutualist, bacteria must sense the presence of and migrate towards a host, compete for space and nutrients with other microbes, evade the host immune system, and change their physiology to enable long-term host association. We primarily focus on well-studied taxa, such as Pseudomonas, that associate with diverse model plant and animal hosts, with far-ranging symbiotic outcomes. Given the importance of opportunistic pathogens and chronic infections in both human health and agriculture, understanding the mechanisms that facilitate symbiotic relationships between bacteria and their hosts will help inform the development of disease treatments for both humans, and the plants we eat.

Indexed as

PlantsSymbiosisAnimalsBacteriaHumansbiofilmcolonizationhost associationhost-microbe interactionsouter membrane modificationsPseudomonasSymbiosistwo-component signaling

Identifiers

PMID36521845
PMCPMC10719066
OpenAlexW4311663101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.