Evidence map›Paper›PMID 36520948›Full record

ArticleThe Journal of organic chemistry2023

Acyl Amidines by Pd-Catalyzed Aminocarbonylation: One-Pot Cyclizations and

Jonas Rydfjord, Sara Roslin, Tamal Roy, Alaa Abbas, Marc Y Stevens, Luke R Odell

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Palladium-Mediated Synthesis of [Carbonyl-The Journal of organic chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jonas RydfjordDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.
Sara RoslinDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.ORCID 0000-0003-0199-5196
Tamal RoyDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.
Alaa AbbasDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.
Marc Y StevensDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.
Luke R OdellDepartment of Medicinal Chemistry, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden.ORCID 0000-0001-7658-5103
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A protocol for the carbonylative synthesis of acyl amidines from aryl halides, amidines, and carbon monoxide catalyzed by Pd(0) is reported herein. Notably, carbon monoxide is generated ex situ from a solid CO source, and several productive palladium ligands were identified with complementary benefits and substrate scope. Furthermore, sequential one-pot, two-step protocols for the synthesis of 1,2,4-triazoles and 1,2,4-oxadiazoles via acyl amidine intermediates are reported. In addition, this approach was extended to isotopic labeling using [

Identifiers

PMID36520948
PMCPMC10127271
OpenAlexW2768712421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.