Evidence map›Paper›PMID 36520688›Full record

ReviewPLoS neglected tropical diseases2022

The Cryptococcus gattii species complex: Unique pathogenic yeasts with understudied virulence mechanisms.

Lamin Saidykhan, Chinaemerem U Onyishi, Robin C May

Open access · goldAbstract readReview
In one paragraph

Review in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Pathogenic diversity ofCell surface (Amsterdam, Netherlands) · 2025
    Article
  5. mBio · 2025
    Article
  6. Genomic Characterization ofVeterinary sciences · 2025
    Article
  7. Review
  8. Review
  9. Cryptococcal nutrient acquisition and pathogenesis: dining on the host.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  10. Epidemiological Study ofVeterinary sciences · 2025
    Article
  11. Article
  12. Donor-derived Cryptococcus gattii complex infection after liver transplantation.Revista da Sociedade Brasileira de Medicina Tropical · 2025
    Review
  13. Review
  14. Article
  15. Models for Inducing Experimental Cryptococcosis in Mice.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lamin SaidykhanInstitute of Microbiology & Infection and School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Chinaemerem U OnyishiInstitute of Microbiology & Infection and School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
Robin C MayInstitute of Microbiology & Infection and School of Biosciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.ORCID 0000-0001-5364-1838
University of Birmingham · GBUniversity of the Gambia · GM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Members of Cryptococcus gattii/neoformans species complex are the etiological agents of the potentially fatal human fungal infection cryptococcosis. C. gattii and its sister species cause disease in both immunocompetent and immunocompromised hosts, while the closely related species C. neoformans and C. deneoformans predominantly infect immunocompromised hosts. To date, most studies have focused on similarities in pathogenesis between these two groups, but over recent years, important differences have become apparent. In this review paper, we highlight some of the major phenotypic differences between the C. gattii and neoformans species complexes and justify the need to study the virulence and pathogenicity of the C. gattii species complex as a distinct cryptococcal group.

Indexed as

CryptococcosisCryptococcus gattiiCryptococcus neoformansHumansImmunocompromised HostVirulence

Identifiers

PMID36520688
PMCPMC9754292
OpenAlexW4311557147

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.