Evidence map›Paper›PMID 36520317›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2023

A deep-learning based system using multi-modal data for diagnosing gastric neoplasms in real-time (with video).

Hongliu Du, Zehua Dong, Lianlian Wu, Yanxia Li, Jun Liu, Chaijie Luo, Xiaoquan Zeng, Yunchao Deng, Du Cheng, Wenxiu Diao and 5 more

Open access · bronzeAbstract readVideo-Audio Media
PubMed Publisher
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Artificial Intelligence for Endoscopic Diagnosis of Gastric Premalignant Lesions.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Hallucination-Aware Multimodal Benchmark for Gastrointestinal Image Analysis with Large Vision-Language Models.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. [Research progress on endoscopic image diagnosis of gastric tumors based on deep learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Review
  12. Review
  13. Observational
  14. Review
  15. ENDOANGELTherapeutic advances in gastroenterology · 2023
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Hongliu Du *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Zehua Dong *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Lianlian Wu *Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Yanxia LiDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Jun LiuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Chaijie LuoDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiaoquan ZengDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Yunchao DengDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Du ChengDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Wenxiu DiaoDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Yijie ZhuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Xiao TaoDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Junxiao WangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Chenxia ZhangDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.
Honggang YuDepartment of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China. yuhonggang1968@163.com.ORCID 0000-0002-1882-7060
Wuhan University · CN

Funding

Health Commission of Hubei Province WJ202C003Wuhan University 2042021kf0084
6 · The paper itself

Abstract

backgroundWhite light (WL) and weak-magnifying (WM) endoscopy are both important methods for diagnosing gastric neoplasms. This study constructed a deep-learning system named ENDOANGEL-MM (multi-modal) aimed at real-time diagnosing gastric neoplasms using WL and WM data.

methodsWL and WM images of a same lesion were combined into image-pairs. A total of 4201 images, 7436 image-pairs, and 162 videos were used for model construction and validation. Models 1-5 including two single-modal models (WL, WM) and three multi-modal models (data fusion on task-level, feature-level, and input-level) were constructed. The models were tested on three levels including images, videos, and prospective patients. The best model was selected for constructing ENDOANGEL-MM. We compared the performance between the models and endoscopists and conducted a diagnostic study to explore the ENDOANGEL-MM's assistance ability.

resultsModel 4 (ENDOANGEL-MM) showed the best performance among five models. Model 2 performed better in single-modal models. The accuracy of ENDOANGEL-MM was higher than that of Model 2 in still images, real-time videos, and prospective patients. (86.54 vs 78.85%, P = 0.134; 90.00 vs 85.00%, P = 0.179; 93.55 vs 70.97%, P < 0.001). Model 2 and ENDOANGEL-MM outperformed endoscopists on WM data (85.00 vs 71.67%, P = 0.002) and multi-modal data (90.00 vs 76.17%, P = 0.002), significantly. With the assistance of ENDOANGEL-MM, the accuracy of non-experts improved significantly (85.75 vs 70.75%, P = 0.020), and performed no significant difference from experts (85.75 vs 89.00%, P = 0.159).

conclusionsThe multi-modal model constructed by feature-level fusion showed the best performance. ENDOANGEL-MM identified gastric neoplasms with good accuracy and has a potential role in real-clinic.

Indexed as

Deep LearningStomach NeoplasmsEndoscopy, GastrointestinalHumansProspective StudiesDeep learningGastric neoplasmsMulti-modal fusionWeak magnification endoscopy

Identifiers

PMID36520317
OpenAlexW4311582301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.