Evidence map›Paper›PMID 36520252›Full record

SynthesisReviews in endocrine & metabolic disorders2023

Periconceptional biomarkers for maternal obesity: a systematic review.

Batoul Hojeij, Melek Rousian, Kevin D Sinclair, Andras Dinnyes, Régine P M Steegers-Theunissen, Sam Schoenmakers

Full text readSystematic Review
In one paragraph

Synthesis in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. FIGO good practice recommendations on anemia in pregnancy, to reduce the incidence and impact of postpartum hemorrhage (PPH).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Guideline
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Batoul HojeijDepartment of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.ORCID 0000-0002-3262-0293
Melek RousianDepartment of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.ORCID 0000-0002-3008-2567
Kevin D SinclairSchool of Biosciences, Sutton Bonnington Campus, University of Nottingham, Leicestershire, LE12 6HD, UK.ORCID 0000-0002-6375-215X
Andras DinnyesBioTalentum Ltd., Godollo, 2100, Hungary.ORCID 0000-0003-3791-2583
Régine P M Steegers-TheunissenDepartment of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands.ORCID 0000-0002-4353-5756
Sam SchoenmakersDepartment of Obstetrics and Gynecology, Erasmus MC, University Medical Center, Rotterdam, 3015GD, The Netherlands. s.schoenmakers@erasmusmc.nl.ORCID 0000-0002-0316-6159

Funding

Biotechnology and Biological Sciences Research Council BB/K017810/1
6 · The paper itself

Abstract

Periconceptional maternal obesity is linked to adverse maternal and neonatal outcomes. Identifying periconceptional biomarkers of pathways affected by maternal obesity can unravel pathophysiologic mechanisms and identify individuals at risk of adverse clinical outcomes. The literature was systematically reviewed to identify periconceptional biomarkers of the endocrine, inflammatory and one-carbon metabolic pathways influenced by maternal obesity. A search was conducted in Embase, Ovid Medline All, Web of Science Core Collection and Cochrane Central Register of Controlled Trials databases, complemented by manual search in PubMed until December 31

Indexed as

LeptinPregnancy in ObesityAdiponectinBiomarkersCarbonChorionic GonadotropinC-Reactive ProteinFemaleHumansInfant, NewbornInsulinObesityPregnancyProgesteroneAdiponectinBiomarkersCarbonChorionic GonadotropinC-Reactive ProteinInsulinLeptinProgesteroneBiomarkerBody mass indexObesityPericonceptional period

Identifiers

PMID36520252
PMCPMC10023635

What OpenQuestion holds

Textfull text, public
LicenceCC BY
reference markers read53
measurements read57
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.