Evidence map›Paper›PMID 36520238›Full record

ArticlePflugers Archiv : European journal of physiology2023

Renal angiotensin I-converting enzyme-deficient mice are protected against aristolochic acid nephropathy.

Annett Juretzko, Antje Steinbach, Jeannine Witte, Anke Hannemann, Bärbel Miehe, Florian Siegerist, Carmen Wolke, Sylvia Stracke, Rainer Rettig

Open access · hybridAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Annett JuretzkoInstitute of Physiology, University Medicine, Greifswald, Germany. annett.juretzko@med.uni-greifswald.de.ORCID 0000-0002-8554-6082
Antje SteinbachInstitute of Physiology, University Medicine, Greifswald, Germany.
Jeannine WitteInstitute of Physiology, University Medicine, Greifswald, Germany.
Anke HannemannInstitute of Clinical Chemistry and Laboratory Medicine and DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine, Greifswald, Germany.
Bärbel MieheInstitute of Anatomy and Cell Biology, University Medicine, Greifswald, Germany.
Florian SiegeristInstitute of Anatomy and Cell Biology, University Medicine, Greifswald, Germany.
Carmen WolkeInstitute of Medical Biochemistry and Molecular Biology, University Medicine, Greifswald, Germany.
Sylvia StrackeClinic for Internal Medicine A, University Medicine, Greifswald, Germany.
Rainer RettigInstitute of Physiology, University Medicine, Greifswald, Germany.
Universitätsmedizin Greifswald · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The renal renin-angiotensin system (RAS) is involved in the development of chronic kidney disease. Here, we investigated whether mice with reduced renal angiotensin I-converting enzyme (ACE

Indexed as

Peptidyl-Dipeptidase ARenal Insufficiency, ChronicAngiotensin-Converting Enzyme 2Angiotensin IAngiotensin IIAnimalsAristolochic AcidsMiceMice, Inbred C57BLPeptide FragmentsProto-Oncogene MasRenin-Angiotensin SystemAngiotensin-Converting Enzyme 2Angiotensin IAngiotensin IIaristolochic acid IAristolochic AcidsPeptide FragmentsPeptidyl-Dipeptidase AProto-Oncogene MasAngiotensin (1–7)Angiotensin I-converting enzyme 2Aristolochic acid IChronic kidney diseaseRenin-angiotensin system

Identifiers

PMID36520238
PMCPMC9908662
OpenAlexW4311588606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.