ArticleNeurourology and urodynamics2023
Effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction.
Article in Neurourology and urodynamics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- The Voided Volume Transit Point: A Novel Functional Biomarker for Staging Bladder Outlet Obstruction?The Journal of urology · 2026Article
- Lower Urinary Tract Symptoms in Patients with Congenital Genitourinary Anomalies.Current urology reports · 2025Review
- Revisiting voided volume: the forgotten parameter in assessing BOO surgical outcomes.World journal of urology · 2024Article
- Recent advances in the diagnosis of bladder outlet obstruction in men.Bladder (San Francisco, Calif.) · 2024Review
- Effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction.Neurourology and urodynamics · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionBladder outlet obstruction alters detrusor contractility, reducing the bladder's ability to respond to large filling with a risk of urinary retention. The objective was to assess the effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction.
methodsA prospective multicenter study in two pelviperineology departments. Male patients eligible for urodynamics (IPSS score > 7) were included from January to July 2022. In case of absence of bladder outlet obstruction on pressure-flow studies, they were secondarily excluded. The primary endpoint was the maximum isometric detrusor pressure during a stop-test, corresponding to detrusor contractility, measured at 3 filling volumes (50%, 75%, and 100% of cystometric capacity).
resultsFifty-two patients performed urodynamics, of whom 12 were excluded because of lack of obstruction or inability to perform the stop-test. Detrusor contractility was significantly higher for a 75% bladder filling than 50% and for a 75% filling than 100%, with a mean difference of 19.5; confidence interval (CI) 95% [14.3; 24.8] and 12.2; CI 95% [6.9; 17.5] cmH
conclusionIn case of bladder outlet obstruction in men, detrusor contractility depends on bladder filling volume, with reduced contractility when the bladder was underfilled or overfilled. This phenomenon could help to explain the mechanisms of urinary retention in men with bladder outlet obstruction.
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