Evidence map›Paper›PMID 36519599›Full record

ArticlePediatric blood & cancer2023

Imaging of pediatric brain tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee/ASPNR White Paper.

Alok Jaju, Yi Li, Hisham Dahmoush, Nicholas G Gottardo, Suzanne Laughlin, David Mirsky, Ashok Panigrahy, Noah D Sabin, Dennis Shaw, Phillip B Storm and 3 more

Open access · greenAbstract readConsensus Statement
In one paragraph

Article in Pediatric blood & cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Guideline
  2. Long-term outcomes of pediatric medulloblastoma before routine molecular classification: a 20-year single-center cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Verschlimmbesserung: Craniospinal Radiotherapy Is Essential in WNT Medulloblastoma Patients.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 3 countries.

Alok JajuDepartment of Medical Imaging, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Yi LiUCSF Department of Radiology and Biomedical Imaging, San Francisco, California, USA.
Hisham DahmoushDepartment of Radiology, Lucile Packard Children's Hospital at Stanford, Palo Alto, California, USA.
Nicholas G GottardoDepartment of Paediatric and Adolescent Oncology and Haematology, Perth Children's Hospital, Brain Tumour Research Programme, Telethon Kids Institute, Perth, Western Australia, Australia.
Suzanne LaughlinDepartment of Diagnostic Imaging, The Hospital for Sick Children and Department of Medical Imaging, University of Toronto, Toronto, Ontario, Canada.
David MirskyDepartment of Radiology, Children's Hospital Colorado, Aurora, Colorado, USA.
Ashok PanigrahyDepartment of Radiology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Noah D SabinDepartment of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Dennis ShawDepartment of Radiology, Seattle Children's Hospital, Seattle, Washington, USA.
Phillip B StormDivision of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Tina Young PoussaintDepartment of Radiology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Zoltan PatayDepartment of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Aashim BhatiaDepartment of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Children's Hospital of Philadelphia · USSt. Jude Children's Research Hospital · USChildren's Hospital of Pittsburgh · USHarvard University · USHospital for Sick Children · CALucile Packard Children's Hospital · USLurie Children's Hospital · USSeattle Children's Hospital · USThe Kids Research Institute Australia · AUUniversity of California, San Francisco · USUniversity of Colorado Denver · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
The Pediatric Brain Tumor Consortium (PBTC)U01CA081457 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI BOYETT, JAMES MILFORD · 1999 to 2013
$29.2M
NCI NIH HHS U01 CA081457NCI NIH HHS U10 CA180886
6 · The paper itself

Abstract

Tumors of the central nervous system are the most common solid malignancies in children and the most common cause of pediatric cancer-related mortality. Imaging plays a central role in diagnosis, staging, treatment planning, and response assessment of pediatric brain tumors. However, the substantial variability in brain tumor imaging protocols across institutions leads to variability in patient risk stratification and treatment decisions, and complicates comparisons of clinical trial results. This White Paper provides consensus-based imaging recommendations for evaluating pediatric patients with primary brain tumors. The proposed brain magnetic resonance imaging protocol recommendations balance advancements in imaging techniques with the practicality of deployment across most imaging centers.

Indexed as

Brain NeoplasmsSurface Plasmon ResonanceBrainCentral Nervous SystemChildHumansMagnetic Resonance Imagingbrain tumorscomputed tomographymagnetic resonance imagingpediatric

Identifiers

PMID36519599
PMCPMC10466217
OpenAlexW4311524730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.