Evidence map›Paper›PMID 36519571›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Effects of extremity trauma on physiological responses to hemorrhage in conscious rats.

Harold G Klemcke, Mariam L Calderon, Kathy L Ryan, Lusha Xiang, Carmen Hinojosa-Laborde

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Harold G KlemckeUS Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.ORCID 0000-0002-9499-0599
Mariam L CalderonUS Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.
Kathy L RyanUS Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.
Lusha XiangUS Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.ORCID 0000-0002-7255-1640
Carmen Hinojosa-LabordeUS Army Institute of Surgical Research, Joint Base San Antonio-Fort Sam Houston, San Antonio, Texas.ORCID 0000-0001-7104-3305
United States Army Institute of Surgical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although physiological responses to hemorrhage are well-studied, hemorrhage is often accompanied by trauma, and it remains unclear how injury affects these responses. This study examined effects of extremity trauma on cardiorespiratory responses and survival to moderate (37%; H-37) or severe (50%; H-50) hemorrhage in rats. Transmitter and carotid catheter implantation and extremity trauma (fibular fracture and muscle injury) were conducted 2 wk, 24 h, and 90 min, respectively, before conscious hemorrhage. Mean arterial pressure (MAP) and heart rate (HR; via telemetry), and respiration rate (RR), minute volume (MV), and tidal volume (TV; via plethysmography) were measured throughout the 25 min hemorrhage and remainder of the 4 h observation period. There were four groups:

Indexed as

HemorrhagePlethysmographyAnimalsExtremitiesHeart RateModels, AnimalRatscardiovascularhemorrhagerespirationtrauma

Identifiers

PMID36519571
PMCPMC9829477
OpenAlexW4311611853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.