Evidence map›Paper›PMID 36519532›Full record

Trial reportPhlebology2023

Effect of pneumatic compression device and stocking use on symptoms and quality of life in women with lipedema: A proof-in-principle randomized trial.

Thomas Wright, Crystal D Scarfino, Ellen M O'Malley

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Phlebology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Review
  5. Article
  6. Lipedema Reduction Surgery Outcomes and Comorbidities: A Retrospective Study.Plastic and reconstructive surgery. Global open · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas WrightLaser Lipo and Vein Center, O'Fallon, MO, USA.ORCID 0000-0003-4900-2800
Crystal D ScarfinoLaser Lipo and Vein Center, O'Fallon, MO, USA.
Ellen M O'MalleyO'Malley Medical Communications, LLC, Victoria, MN, USA.ORCID 0000-0002-3751-764X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDoes short-term use of pneumatic compression devices (PCD) and off-the-shelf compression alleviate symptoms and improve quality of life in women with lipedema and secondary lipolymphedema?

methodsProspective, randomized controlled, industry-sponsored, proof-in-principle study comparing PCD plus conservative care (PCD+CC) to CC alone (control). Adult females with bilateral lipedema and secondary lymphedema were randomized to PCD+CC or CC. Outcome measures were lower limb and truncal circumferential measurements, bioimpedance, and quality-of-life, symptom, and pain intensity questionnaires.

resultsBoth groups experienced improvements in leg circumference and bioimpedance with more improvement in the PCD+CC group than the CC group. Pain scores of the SF-36 survey and numerical rating scales were improved in the PCD+CC group. Wong-Baker Faces scores showed trends toward improvement in both groups.

conclusionsThis proof-in-principle study supports conservative management with graduated compression and with or without PCD for improvement in leg circumference, bioimpedance measurements, and pain in patients with lipedema.

Indexed as

LipedemaLymphedemaAdultFemaleHumansIntermittent Pneumatic Compression DevicesPainProspective StudiesQuality of Lifebioimpedancelimb circumferencePROMISrandomized controlled trialSF-36

Identifiers

PMID36519532
PMCPMC9902958
OpenAlexW4311582695

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.