ArticleThe EMBO journal2023
Mass-Spec, Cryo-EM and AI join forces for a close look at the transporter complex in cilia.
Article in The EMBO journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Mass-Spec, Cryo-EM and AI join forces for a close look at the transporter complex in cilia.The EMBO journal · 2023Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The intraflagellar transport (IFT) complex transports components between the cytoplasm and the ciliary tip. Two studies now report on the atomic structure of IFT-B, the core of IFT, using cutting-edge technology, such as cross-linking mass spectrometry (MS), cryo-electron tomography (cryo-ET) and Alphafold2-enabled AI-based folding prediction. The 3D structure of IFT-B reveals how the 15 component proteins are arranged to stabilize this gigantic complex and suggests a dynamic interplay between the proteins.
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Registered trials
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