SynthesisBrain and behavior2023
Association between insomnia and frailty in older population: A meta-analytic evaluation of the observational studies.
Synthesis in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Efficacy and safety of holographic scraping in insomnia: A systematic review and meta-analysis of randomized controlled trials.Medicine · 2026Pooled it
- Factors associated with frailty in older people: an umbrella review.BMC geriatrics · 2024Pooled it
- Epidemiology of insomnia disorder in older persons according to the Diagnostic and Statistical Manual of Mental Disorders: a systematic review and meta-analysis.European geriatric medicine · 2023Pooled it
- Association between insomnia and frailty in older population: A meta-analytic evaluation of the observational studies.Brain and behavior · 2023Pooled it
- Frailty-Driven Prediction of Inpatient Obstructive Sleep Apnea and Related Sleep Disorder Diagnoses Using Explainable AI.Biomedicines · 2026Article
- J-shaped relationship between physical activity and frailty risk in adults with sleep disorders: the additional protective role of the weekend warrior pattern.Scientific reports · 2026Article
- Development and validation of a nomogram for identifying pre-frailty risk in middle-aged and elderly maintenance hemodialysis patients: a cross-sectional study.BMC nephrology · 2026Article
- Impact of a Multidimensional Community-Based Intervention on the Feeling of Unwanted Loneliness and Its Consequences: A Quasi-Experimental Study.Healthcare (Basel, Switzerland) · 2025Article
- Dietary and health risk behaviors for metabolic diseases in different age groups: a cross-sectional study in Chongqing, China.BMC public health · 2025Article
- Casual associations between frailty and nine mental disorders: bidirectional Mendelian randomisation study.BJPsych open · 2025Article
- Oral health associates with frailty in Chinese older adults: a chain mediating model of sleep quality and depressive symptoms.Frontiers in public health · 2025Article
- Bidirectional causal associations between frailty measures and sleep disturbances: a two-sample Mendelian randomization study.Nature and science of sleep · 2025Article
- Causal relationship between genetically predicted mental disorders and frailty: a bidirectional and multivariable mendelian randomization study.BMC psychiatry · 2024Article
- To Be Frail or Not to Be Frail: This Is the Question-A Critical Narrative Review of Frailty.Journal of clinical medicine · 2024Review
- Investigating the shared genetic architecture between frailty and insomnia.Frontiers in aging neuroscience · 2024Article
- Mediating effects of depression on sleep disturbance and frailty in older adult type 2 diabetes patients in the community.Frontiers in public health · 2023Article
- Bidirectional Relationship Between Circadian Rhythm and Frailty.Nature and science of sleep · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPoor sleep quality has been suggested as a risk factor of frailty. However, previous studies that evaluated the association between insomnia and frailty in older population showed inconsistent results. We performed a meta-analysis to comprehensively evaluate the association.
methodsObservational studies related to the aim of the meta-analysis were identified by search of PubMed, Embase, and Web of Science databases. A random-effect model incorporating the potential between-study heterogeneity was used to pool the results.
resultsTwelve studies including 16,895 old people contributed to the meta-analysis. Pooled results suggested a significant association between insomnia and frailty in the older population (odds ratio [OR]: 1.95, 95% confidence interval [CI]: 1.52-2.41, p < .001; I
conclusionInsomnia is independently associated with frailty in the older population.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.