ArticleLupus2023
Post-traumatic stress disorder in patients with systemic lupus erythematosus heavily affects quality of life. A cross-sectional web survey-based study.
Article in Lupus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The trial behind it
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Childhood trauma and systemic lupus erythematosus activity in Tunisian patients: exploring the mediating role of post-traumatic stress disorder.Lupus science & medicine · 2026Article
- Influencing factors and path analysis of posttraumatic growth in patients with autoimmune diseases.Frontiers in psychiatry · 2026Article
- Post-traumatic growth and psychological resilience in adolescents with systemic lupus erythematosus: A cross-sectional study.The Journal of international medical research · 2025Article
- The Economic Impact of Post-Traumatic Stress Disorder Among Patients with Systemic Autoimmune Diseases During the COVID-19 Pandemic.International journal of environmental research and public health · 2024Article
- Patient-reported outcome measures for lupus nephritis: content validity of LupusQoL and FACIT-Fatigue.Journal of patient-reported outcomes · 2024Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesNeuropsychiatric symptoms develop in up to 20% of the patients with Systemic Lupus Erythematosus (SLE). Growing evidence is accruing on the association of SLE with Post-traumatic Stress Disorder (PTSD), but little is known about its contribution on patient-reported outcomes. This study focuses on PTSD prevalence in our SLE cohort and on its impact on quality of life.
methodsTrauma and Loss Spectrum - Self Reported (TALS-SR) and Lupus Quality of Life (Lupus QoL) questionnaires were administered via web to the patients with SLE in our cohort, along with questions on demographical and disease-related aspects.
resultsAmong 99 patients who completed the questionnaire, fatigue prevalence was 75% and 31% scored TALS-SR test consistently with PTSD. Patients with PTSD achieved lower scores compared to those without PTSD in three Lupus QoL domains: planning (83.3 vs. 100,
conclusionsPTSD is possibly far more frequent in patients with SLE than in general population and exerts a detrimental influence on quality of life.
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Registered trials
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