Evidence map›Paper›PMID 36518993›Full record

ArticleOxidative medicine and cellular longevity2022

Qihuang Zhuyu Formula Attenuates Atherosclerosis via Targeting PPAR

Mengxi Wang, Qian Xiang, Weixin Sun, Haowen Zhang, Ruijie Shi, Jun Guo, Huaqin Tong, Manlu Fan, Yuhan Ding, Haibo Shi and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Nutrition research and practice · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Mengxi WangDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-4875-9919
Qian XiangDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Weixin SunDepartment of Cardiology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng 224000, China.
Haowen ZhangCollege of Health Preservation and Rehabilitation, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Ruijie ShiDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Jun GuoDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Huaqin TongDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Manlu FanDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Yuhan DingDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Haibo ShiDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Peng YuDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.
Le ShenDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-4150-2897
Qiong WangLaboratory of Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0001-6251-4996
Xiaohu ChenDepartment of Cardiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, China.ORCID https://orcid.org/0000-0002-8261-7770
Nanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At present, due to the limitations of drug therapy targets for atherosclerosis, some patients fail to achieve satisfactory efficacy. Cholesterol efflux dysfunction and endothelial cell inflammation are considered to be important factors in the development of atherosclerosis. Peroxisome proliferator-activated receptor gamma (PPAR

Indexed as

AtherosclerosisDrugs, Chinese HerbalPPAR gammaAnimalsCholesterolEndothelial CellsFoam CellsInflammationLiver X ReceptorsMiceMice, Inbred C57BLMice, Knockout, ApoEMolecular Docking SimulationNF-kappa BCholesterolDrugs, Chinese HerbalLiver X ReceptorsNF-kappa BPPAR gamma

Identifiers

PMID36518993
PMCPMC9744610
OpenAlexW4312012831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.