Evidence map›Paper›PMID 36518694›Full record

ArticleACS medicinal chemistry letters2022

Benzo[

Zian Xue, Huiti Li, Wenhao Xie, Ying Xu, Lu Zhou, Zhi-Bei Qu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. HIF-1 and HIF-2 in cancer: structure, regulation, and therapeutic prospects.Cellular and molecular life sciences : CMLS · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zian XueDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 200120, China.
Huiti LiDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 200120, China.
Wenhao XieDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 200120, China.
Ying XuKey Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Faculty of Basic Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Lu ZhouDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 200120, China.ORCID https://orcid.org/0000-0002-6807-2647
Zhi-Bei QuDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 200120, China.ORCID https://orcid.org/0000-0003-1517-0822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia-inducible factor, also known as HIF, is a transcriptional factor universally found in mammalian cells. HIF-1 is one of the HIF-families and acts as a heterodimer consisting of α and β subunits. It is found to play significant roles in pathologic conditions such as tumor development and metastasis. Here, we first report benzo[

Identifiers

PMID36518694
PMCPMC9743424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.