Evidence map›Paper›PMID 36518444›Full record

ArticleToxicology reports2022

Sub-chronic toxicity study of green peas protein hydrolysate in rats.

Meilinah Hidayat, Sijani Prahastuti, Anggie S Rakasiwi, Sipra Prisilia, Khomaini Hasan

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Brazilin cream fromPeerJ · 2024
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Meilinah HidayatFaculty of Medicine, Universitas Kristen Maranatha Bandung, Jalan Prof Drg Suria Sumantri 65, Bandung 40164, Indonesia.
Sijani PrahastutiFaculty of Medicine, Universitas Kristen Maranatha Bandung, Jalan Prof Drg Suria Sumantri 65, Bandung 40164, Indonesia.
Anggie S RakasiwiFaculty of Medicine, Universitas Kristen Maranatha Bandung, Jalan Prof Drg Suria Sumantri 65, Bandung 40164, Indonesia.
Sipra PrisiliaFaculty of Medicine, Universitas Kristen Maranatha Bandung, Jalan Prof Drg Suria Sumantri 65, Bandung 40164, Indonesia.
Khomaini HasanFaculty of Medicine, Universitas Jenderal Achmad Yani, Jl. Terusan Jenderal Sudirman, PO Box 148, Cimahi, Jawa Barat, Indonesia.
Maranatha Christian University · IDUniversitas Jenderal Achmad Yani · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite green peas protein hydrolysate benefits, very few studies have described the potential toxicity. The acute oral toxicity of green peas protein which hydrolyzed by bromelain at a single dose of 5000 mg/kg BW has been evaluated in Swiss Webster mice and did not produce treatment-related signs of toxicity or mortality in any of the animals tested during the 14-day observation period. The present study aimed was to evaluate the sub-chronic toxicity effects of Protein Hydrolysate Green Peas Bromelain (PHGPB) in Sprague Dawley rats by the regulations of the Indonesian Food and Drug Supervisory Agency 2013. In the repeated dose 28-day oral toxicity study, the administration of 100 mg/kg, 200 mg/kg, and 400 mg/kg/day of green peas protein hydrolysate per body weight revealed no significant difference (

Indexed as

BromelainGreen peasProtein hydrolysateSub-chronic toxicity

Identifiers

PMID36518444
PMCPMC9742815
OpenAlexW4224229690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.