Evidence map›Paper›PMID 36518418›Full record

ArticleToxicology reports2022

Urinary excretion of estrogenic chemicals following consumption of capsule coffee and French press coffee: A crossover study.

Junichi R Sakaki, Anthony A Provatas, Christopher Perkins, Ock K Chun

Abstract read
In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junichi R SakakiDepartment of Nutritional Sciences, University of Connecticut, 27 Manter Rd., Unit 4017, Storrs, CT 06269, USA.
Anthony A ProvatasCenter for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Rd., Storrs, CT 06269, USA.
Christopher PerkinsCenter for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Rd., Storrs, CT 06269, USA.
Ock K ChunDepartment of Nutritional Sciences, University of Connecticut, 27 Manter Rd., Unit 4017, Storrs, CT 06269, USA.

Funding

Assessment of Risk of Exposure to Estrogenic Chemicals via Capsule Coffee ConsumptionR03ES027983 · NIEHS · UNIVERSITY OF CONNECTICUT STORRS · PI CHUN, OCK K. · 2018 to 2019
$160k
NIEHS NIH HHS R03 ES027983
6 · The paper itself

Abstract

Background: Coffee brewed from capsules contain estrogenic chemicals (ECs) that may harm the reproductive system. However, there are no studies investigating whether consuming capsule coffee causes these ECs to present in urine. Objective: Compare the effects of consuming capsule coffee vs. a plastic-free (French press) method on the appearance of ECs in urine. Methods: Participants (n = 30) were randomized to consume 540 mL of capsule or French press coffee once, then switched and consumed the other coffee after washout. Urine samples were collected prior to consumption, at 6 h and 24 h. Coffee and urine samples were analyzed for nine ECs using ultra-performance liquid chromatography with tandem mass spectrometry: bisphenol A (BPA), bisphenol F (BPF), bisphenol S, di(2-ethylhexyl) phthalate (DEHP), benzophenone, 4-nonylphenol (4-NP), dibutyl phthalate, caprolactam and dimethyl terephthalate. Results: In coffee samples, BPF (French press: 13.9 ng/mL, capsule: 16.1 ng/mL) and DEHP (capsule: 1.12 ng/mL) were present. In 6 h urine samples, the detection frequency for DEHP was 6.7% in capsule and 13.3% in French press coffee. BPF was detected in only one urine sample post-consumption. Conclusion: Consuming capsule coffee did not increase urinary EC exposure compared to consuming French press coffee.

Indexed as

4-NP, 4-nonylphenolBPA, bisphenol ABP, benzophenoneBPF, bisphenol FBPS, bisphenol SCapsuleCoffeeDBP, dibutyl phthalateDEHP, di(2-ethylhexyl) phthalateDMTP, dimethyl terephthalateEC, estrogenic chemicalEstrogenic chemicalHPLC, high-performance liquid chromatographyInterventionLOD, limit of detectionPlasticUPLC-MS/MS, ultra-performance liquid chromatography with tandem mass spectrometry

Identifiers

PMID36518418
PMCPMC9742817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.