Evidence map›Paper›PMID 36518405›Full record

ArticleToxicology reports2022

Evaluating effect of acrylamide and ascorbic acid on oxidative stress and apoptosis in ovarian tissue of wistar rat.

Amir Masoud Firouzabadi, Maryam Imani, Fatemeh Zakizadeh, Nadia Ghaderi, Fatemeh Zare, Maryam Yadegari, Majid Pourentezari, Farzaneh Fesahat

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Amir Masoud FirouzabadiReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Maryam ImaniReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Fatemeh ZakizadehReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nadia GhaderiReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Fatemeh ZareReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Maryam YadegariReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Majid PourentezariReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Farzaneh FesahatReproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Shahid Sadoughi University of Medical Sciences and Health Services · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acrylamide is one of the undesirable compounds created in food, which leads to oxidative stress. Under normal conditions of the body, there is a balance between the production and elimination of free radicals. Imbalance in this process causes oxidative stress. Ascorbic acid has antioxidant properties and can be used to prevent oxidative stress damage. In this study, we considered the effect of acrylamide as a substance that causes oxidative stress and ascorbic acid as an antioxidant. In this experiment, 28 rats were separated into 4 groups (n = 7). Mice were fed orally with acrylamide (10 mg/kg), ascorbic acid (200 mg/kg), both acrylamide and ascorbic acid, and water as AR, AA, AR&AA, and control groups, respectively. Blood and ovarian tissue samples were collected after the final feeding and anesthesia for hematological tests. Blood cells, anti-oxidation status and relative expression of

Indexed as

AcrylamideAscorbic acidGene expressionOvarian follicle developmentOxidative stress markersRat

Identifiers

PMID36518405
PMCPMC9742936
OpenAlexW4288078007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.