Evidence map›Paper›PMID 36518381›Full record

ArticleToxicology reports2022

Ki-67 pulmonary immunoreactivity in silver nanoparticles toxicity: Size-rate dependent genotoxic impact.

Sanaa A Ali, Mai O Kadry, Olfat Hammam, Sohair A Hassan, Rehab M Abdel-Megeed

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sanaa A AliTherapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, El Buhouth St., Dokki, Cairo 12622, Egypt.
Mai O KadryTherapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, El Buhouth St., Dokki, Cairo 12622, Egypt.
Olfat HammamPathology Department, Theodor Bilharz Research Institute, Egypt.
Sohair A HassanTherapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, El Buhouth St., Dokki, Cairo 12622, Egypt.
Rehab M Abdel-MegeedTherapeutic Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Center, El Buhouth St., Dokki, Cairo 12622, Egypt.
Theodor Bilharz Research Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Engineered nanoparticles have been recently utilized in numerous domains particularly, silver nanoparticles (AgNPs). Nonetheless, the possible side effects resulting from AgNPs exposure are not fully clarified. The present study was designed to clarify the toxicity of AgNPs on lung tissue. Furthermore, therapeutic impact of Practical applications: Due to the expansion of AgNPs applications, it is urgent to investigate their toxic impact associated with release of free silver ions. Different particle sizes of AgNPs can induce various alterations in cellular biochemical parameters, mRNA gene expression, histopathological and immunohistopathological examination. Herein, this natural products extracts are used for the first time as promising therapeutic regimen to ameliorate the toxic effect in AgNPs intoxicated lung tissue in mice model as a result of the bioactive metabolites, especially flavonoids and polyphenolic compounds.

Indexed as

AgNPsCasimiroa edulisGlycosmis pentaphyllaKi-67Matrix metalloproteinaseSurvivin

Identifiers

PMID36518381
PMCPMC9742976
OpenAlexW4297895688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.