Evidence map›Paper›PMID 36518362›Full record

ArticleCase reports in nephrology and dialysis

Primary Sclerosing Cholangitis and Amyloid A Amyloidosis: Association or Coincidence?

Rosanna Lacetera, Letizia Roggero, Paolo Vercelloni, Martina Uzzo, Marco Carbone, Pietro Invernizzi, Vincenzo L'Imperio, Federico Pieruzzi, Renato Alberto Sinico

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in nephrology and dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Rosanna LaceteraaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Letizia RoggeroaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Paolo VercellonibNephrology and Dialysis Unit, San Gerardo Hospital, Monza, Italy.
Martina UzzoaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Marco CarbonecDivision of Gastroenterology, Department of Medicine and Surgery, Centre for Autoimmune Liver Diseases, University of Milano-Bicocca, Milan, Italy.
Pietro InvernizzicDivision of Gastroenterology, Department of Medicine and Surgery, Centre for Autoimmune Liver Diseases, University of Milano-Bicocca, Milan, Italy.
Vincenzo L'ImperioeDepartment of Medicine and Surgery, Pathology, ASST Monza, University of Milano-Bicocca, Monza, Italy.
Federico PieruzziaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Renato Alberto SinicoaDepartment of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
University of Milano-Bicocca · ITAzienda Ospedaliera San Gerardo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AA amyloidosis may complicate several chronic inflammatory conditions. From a clinical point of view, causality between inflammatory pathology and AA amyloidosis can be assumed because of the data described in the literature; some of the best known include rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, and chronic infections. Singles cases of inflammatory diseases have been found at AA amyloidosis. Causality becomes more plausible if at least two different cases with AA amyloidosis are both found to have the same rare inflammatory disease. We describe the case of a patient with primary sclerosing cholangitis (PSC) with development of AA amyloidosis conditioning a nephrotic syndrome, likely secondary to failure to control the chronic inflammatory process. Only two cases in the literature describe the association of this rare disease and the appearance of AA amyloidosis. The treatment of AA amyloidosis consists in treating the underlying inflammatory disorder; to date, few effective treatments are available for PSC. Therefore, and in view of the limited data in the literature, we believe it is important to describe its association.

Indexed as

AA amyloidosisNephrotic syndromePrimary sclerosing cholangitis

Identifiers

PMID36518362
PMCPMC9743140
OpenAlexW4301187619

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.