Evidence map›Paper›PMID 36518350›Full record

ArticleFrontiers in rehabilitation sciences2022

Development of a behavioural intervention for cognitive fatigability in multiple sclerosis: Protocol for a pilot and feasibility study.

Lisa A S Walker, Jason A Berard, Tamanna Islam, Lara A Pilutti, Sarah A Morrow, Marcia Finlayson

Open access · goldAbstract read
In one paragraph

Article in Frontiers in rehabilitation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Lisa A S WalkerDepartment of Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Jason A BerardDepartment of Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Tamanna IslamDepartment of Neuroscience, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Lara A PiluttiUniversity of Ottawa Brain and Mind Research Institute, University of Ottawa, Ottawa, ON, Canada.
Sarah A MorrowMS Clinic, London Health Sciences Centre, London, ON, Canada.
Marcia FinlaysonSchool of Rehabilitation Therapy, Queen's University, Kingston, ON, Canada.
University of Ottawa · CALondon Health Sciences Centre · CAOttawa Hospital Research InstituteQueen's University · CAuOttawa Brain and Mind Research Institute

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Up to 90% of people with multiple sclerosis (PwMS) subjectively report fatigue as one of their worst symptoms. Fatigability is an objectively measured component of fatigue. Cognitive fatigability (CF) is a breakdown in task performance following sustained cognitive effort. There is a paucity of interventions targeting CF in MS. The prior success of behavioural interventions at improving subjective fatigue suggests that their adaptation may yield similar results for CF. Given the relationship between CF, sleep quality, and mood, a behavioural intervention targeting these factors, such as cognitive behavioural therapy (CBT), is warranted. Given the multidimensional nature of fatigue, a multifaceted approach targeting lifestyle factors and coping (e.g., fatigue management education supplemented by CBT for insomnia and exercise) might prove efficacious. Aim: We describe a protocol for a pilot feasibility study to design and implement a multi-dimensional behavioural intervention to improve CF in PwMS. Methods: Conclusion: The long-term goal is to ensure that PwMS have access to effective interventions in real-world settings to improve quality of life and enhance their ability to participate in cognitively demanding activities that they enjoy.

Indexed as

cognitioncognitive fatigabilitydepressionexercisefatigueinterventionmultiple sclerosisneuropsychology

Identifiers

PMID36518350
PMCPMC9742940
OpenAlexW4309307624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.