ArticleBMC geriatrics2022
Estimated glucose disposal rate and risk of cardiovascular disease: evidence from the China Health and Retirement Longitudinal Study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- The effects of intermittent fasting on BMI, fasting blood glucose, and blood pressure in women with overweight or obesity: a systematic review and meta-analysis with dose-response relationships.Frontiers in nutrition · 2026Pooled it
- Estimated glucose disposal rate and cardiovascular disease risk: a meta-analysis of cohort studies.Frontiers in endocrinology · 2025Pooled it
- Estimated glucose disposal rate and microvascular complications of diabetes mellitus type I: A systematic review and meta-analysis.Diabetes & vascular disease researchPooled it
- Outcomes With Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Baseline Insulin Resistance.Diabetes care · 2024Trial
- Article
- Lipoprotein(a) and atherosclerosis risk across estimated glucose disposal rate strata: evaluating synergistic predictive utility.Lipids in health and disease · 2026Article
- Combined associations of the metabolic score for insulin resistance and estimated glucose disposal rate with cardio-renal-metabolic multimorbidity: evidence from two large population studies.BMC cardiovascular disorders · 2026Article
- Depression trajectory modifies the association between estimated glucose disposal rate and incident stroke: a prospective cohort study.BMC cardiovascular disorders · 2026Article
- Non-insulin-dependent insulin resistance surrogate indexes for predicting chronic kidney disease in diabetic individuals: a prospective cohort study.BMC endocrine disorders · 2026Article
- Associations between estimated glucose disposal rate and peripheral artery disease: evidence from the UK Biobank and NHANES.Nutrition & metabolism · 2026Article
- Glucose Disposal Rate: A Novel Measure of Insulin Resistance Associated With Myocardial Fibrosis and Incident Heart Failure.Journal of the American Heart Association · 2026Article
- Article
- Joint association of lung function and physical activity with risk of incident stroke among the US and Chinese adults.BMC public health · 2026Article
- Prognostic effect of estimated glucose disposal rate on all-cause and cardiovascular mortality among individuals cardiovascular-kidney-metabolic syndrome.Diabetology & metabolic syndrome · 2026Article
- Association between estimated glucose disposal rate and heart disease events in adults with overweight or obesity: a prospective cohort study.Journal of translational medicine · 2026Article
- The association of estimated glucose disposal rate with white matter hyperintensities: A large prospective cohort study.The journal of prevention of Alzheimer's disease · 2026Article
- Risk Prediction of Edentulism in Chinese Adults: Insights From the China Health and Retirement Longitudinal Study (CHARLS).International dental journal · 2026Article
- Association of estimated glucose disposal rate and body mass index with stroke risk in middle-aged and elderly populations: evidence from two cohort studies.BMC neurology · 2026Article
- Association of estimated glucose disposal rate with erectile dysfunction: mediating role of neutrophil-to-lymphocyte ratio.Food & nutrition research · 2026Article
- Predicting Stroke Incidence Using Estimated Glucose Disposal Rate Index in the Population with Cardiovascular-Kidney-Metabolic Syndrome Stage 0-3 in the Chinese Middle-Aged and Elderly Population.Cardiorenal medicine · 2026Observational
12 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectivesPrevious studies had reported that insulin resistance (assessed by estimated glucose disposal rate; eGDR) was associated with higher risk of cardiovascular events (CVD) in diabetes patients. The aim of present study was to investigate the potential association between eGDR and CVD in general population.
methodsThe China Health and Retirement Longitudinal Study with 8,267 individuals were included in analysis. Participants were divided into four subgroups according to eGDR quartile. Cox proportional hazards regression models were used to examine the associations of eGDR with CVD (stroke or cardiac events).
resultsDuring 6 years of follow-up, a total of 1,476 respondents experienced a CVD (494 stroke and 1,110 cardiac events). In multivariable-adjusted analyses, the corresponding hazard ratio (95% confidence intervals) for the highest eGDR versus lowest quartile of eGDR was 0.58(0.49-0.67) for CVD. Each 1-SD increase of eGDR was associated with 16% (HRs = 0.84; 0.79-0.88) decreased risk of CVD. There was also a significant linear association between eGDR and CVD (P for linearity < 0.001). Similar associations were also found between eGDR and stroke and cardiac events.
conclusionA higher eGDR (a measure of insulin resistance) was associated with a decreased risk of CVD, stroke and cardiac events in general Chinese population, suggesting that eGDR could be considered as a preferential predictor and treatment target of CVD. Future well-designed prospective clinical studies are needed to verify our findings and to assess the effect of eGDR interventions in CVD prevention and therapy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.