SynthesisSurgical endoscopy2023
Endoscopic full-thickness resection for upper gastrointestinal tract lesions: a systematic review and meta-analysis.
Synthesis in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- The efficacy and safety of submucosal tunnel endoscopic resection for the treatment of upper gastrointestinal submucosal tumors: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Safety of Early Diet After Endoscopic Full-Thickness Resection of Gastric Tumor: A Propensity Match Analysis.Digestive diseases and sciences · 2026Article
- Endoscopic Full-Thickness Resection for Gastrointestinal Subepithelial and Epithelial Neoplasia: Current Status, Indications, and Technical and Oncological Challenges-A Multispecialty Perspective.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Review
- Reverse Endoscopic Full-Thickness Resection for Gastric Submucosal Tumors With a Predominant Extraluminal Growth Pattern.Clinical and translational gastroenterology · 2026Article
- Endoscopic full-thickness resection of upper gastrointestinal stromal tumors: a retrospective study from a large tertiary hospital in China.Surgical endoscopy · 2026Article
- Case Report: Cross-overlapping multi-purse-string closure of a large gastric wall defect after endoscopic full-thickness resection.Frontiers in medicine · 2026Article
- Endoscopic full-thickness resection for the treatment of gastric gastrointestinal stromal tumors.Clinical endoscopy · 2026Review
- Risk factors with nomogram construction for moderate to severe pain after endoscopic full-thickness resection.World journal of gastroenterology · 2025Article
- Advancements in Endoscopic Treatment for Gastric Subepithelial Tumors.Gut and liver · 2025Review
- Ligation-assisted endoscopic full-thickness resection combined with preloaded sutures for tiny mesenchymal tumors of the gastric fundus.Endoscopy · 2024Article
- Robotic Platforms for Therapeutic Flexible Endoscopy: A Literature Review.Diagnostics (Basel, Switzerland) · 2024Review
- Endoscopic full-thickness resection using double endoscope-assisted snare traction for a large exophytic gastric subepithelial lesion.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2024Article
- Endoscopic full-thickness resection as a cure for recurrent duodenal adenoma.iGIE : innovation, investigation and insights · 2023Article
- Is the Quantification of Interstitial Cells of Cajal in Gastric Biopsy Samples in Patients With Gastroparesis Ready for Prime Time?Gastroenterology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEndoscopic full-thickness resection (EFTR) is used to resect difficult superficial mucosal lesions and sub-epithelial lesions (SELs). We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of EFTR for upper gastrointestinal tract (GIT) lesions.
methodsWe conducted a comprehensive literature search of MEDLINE, EMBASE, Cochrane, ClinicalTrials.gov, and Scopus databases for studies published in the English language that addressed outcomes of EFTR for upper GIT lesions through November 2021. The weighted pooled rates with the 95% confidence interval (CI) were calculated. Cochran Q test and I statistics were used to calculate heterogeneity.
resultsWe identify 740 articles on the initial search and six studies met the inclusion criteria. 140 patients (45.7% females) with 142 lesions were analyzed. Four studies used the full-thickness resection device (FTRD®). EFTR was performed for 26 adenomas, 97 SELs, six adenocarcinomas, and ten full-thickness biopsies. The overall technical success rate was 86.9% (CI 79.8-94%, I 2 = 38.9%), R0 resection was 80% (CI 67.6-92.3%, I 2 = 75.6%), and the overall adverse events rate was 18.6% (9.8-27.2%, I 2 = 49.4%). Major adverse events included six episodes of major bleeding, three micro-perforations, one large duodenal perforation, and one case of mucosal damage from FTRD®. At 3-6 months follow-up, there were only two cases of recurrence (R0 was not achieved in both).
conclusionEFTR has a high technical and clinical success rate in managing upper GIT lesions with an acceptable safety profile. Large prospective studies comparing EFTR with conventional endoscopic resection techniques are needed.
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