Evidence map›Paper›PMID 36517284›Full record

ArticleTrends in pharmacological sciences2023

Ganaxolone for management of seizures associated with CDKL5 deficiency disorder.

Nelufar Yasmen, Madison N Sluter, Ying Yu, Jianxiong Jiang

Open access · greenAbstract read
In one paragraph

Article in Trends in pharmacological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. GABAFrontiers in pharmacology · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Neuroinflammatory mediators in acquired epilepsy: an update.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Review
  10. Review
  11. Allosteric crosstalk in modular proteins: Function fine-tuning and drug design.Computational and structural biotechnology journal · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nelufar YasmenDepartment of Pharmaceutical Sciences and Drug Discovery Center, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Madison N SluterDepartment of Pharmaceutical Sciences and Drug Discovery Center, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Ying YuDepartment of Pharmaceutical Sciences and Drug Discovery Center, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Jianxiong JiangDepartment of Pharmaceutical Sciences and Drug Discovery Center, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address: jjiang18@uthsc.edu.
University of Tennessee Health Science Center · US

Funding

Inflammatory regulation of neurotrophin signaling in epileptogenesisR01NS100947 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Jianxiong Jiang · 2018 to 2026
$2.8M
Targeting TRPC3 Channels for Epileptic SeizuresR61NS124923 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JIANG, JIANXIONG, LI, WEI · 2022 to 2023
$765k
Targeting Prostaglandin Receptor EP2 for Glioma and Associated EpilepsyR21NS109687 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI JIANG, JIANXIONG · 2019 to 2020
$418k
NINDS NIH HHS R01 NS100947NINDS NIH HHS R21 NS109687NINDS NIH HHS R61 NS124923
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epileptic SyndromesSpasms, InfantileHumansPregnanoloneProtein Serine-Threonine KinasesSeizuresCDKL5 protein, humanganaxolonePregnanoloneProtein Serine-Threonine Kinases

Identifiers

PMID36517284
PMCPMC10031766
OpenAlexW4311420307

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.