Evidence map›Paper›PMID 36517106›Full record

ArticleBMJ open2022

U-PAIN cohort study among patients with chronic pain in specialised pain care: a feasibility study.

Hanna Ljungvall, Anne-Li Lind, Hedvig Zetterberg, Sofia Wagner, Lisa Ekselius, Rolf Karlsten, Markus Heilig, Pernilla Åsenlöf

Abstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanna LjungvallDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden hanna.ljungvall@neuro.uu.se.ORCID 0000-0002-3655-6524
Anne-Li LindDepartment of Neuroscience, Uppsala Universitet, Uppsala, Sweden.
Hedvig ZetterbergDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Sofia WagnerDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Lisa EkseliusDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Rolf KarlstenDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Markus HeiligDepartment of Biomedical and Clinical Sciences, Linkopings universitet, Linkoping, Sweden.
Pernilla ÅsenlöfDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine acceptability of study participation and feasibility of (1) recruitment, (2) data collection and (3) outcome measures for the prospective U-PAIN cohort.

designInternal feasibility study of a prospective cohort. PARTICIPANTS AND

setting64 patients, OUTCOME MEASURES: Acceptability of study participation was measured with a study-specific 10-item Likert scale. A score <3 was considered feasible, for the two items that assessed respondent burden a higher score indicated lesser participant burden and a score >3 was feasible. Recruitment was assessed by participation rates at baseline and retention at the 1-year follow-up, with threshold values for feasibility at 75% and 80%, respectively. Data collection and outcome measures were examined by completions rates of study procedures (90% was considered feasible), sample scores, internal consistency (α>0.70 was considered feasible), and agreement between self-reported data and data retrieved from medical records on opioid use (ICC or κ>0.60 was considered feasible).

resultsAcceptability for study procedures was feasible, but participation rates were low: 25%. The retention rate at 1-year follow-up was 81% for those included in the feasibility study, that is, filling out computerised patient-reported outcome measures, and 65% for those using paper and pencil format. The completion rates for the different data collection methods ranged from 83% to 95%. Agreement between self-reported opioid use and prescribed dose and between opioid use disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), and clinical International Classification of Diseases-10 (ICD-10) diagnoses for opioid dependence were almost perfect (κ=0.91 and κ=0.90, respectively).

conclusionsThis feasibility study has helped to explore and improve methods for recruitment, data collection and use of outcome measures for the U-PAIN cohort. Low participation rate and high refusal rate at baseline is a challenge that needs to be further addressed.

Indexed as

Chronic PainOpioid-Related DisordersAnalgesics, OpioidCohort StudiesFeasibility StudiesHumansProspective StudiesAnalgesics, OpioidHEALTH SERVICES ADMINISTRATION & MANAGEMENTPAIN MANAGEMENTSubstance misuse

Identifiers

PMID36517106
PMCPMC9756188

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.