Evidence map›Paper›PMID 36517064›Full record

ArticleSaudi medical journal2022

Prevalence of transfusion-transmitted infections in Saudi Arabia blood donors: A nationwide, cross-sectional study.

Jawaher Alsughayyir, Yasser Almalki, Imtinan Alburayk, Mohrah Alalshaik, Ibrahim Aljoni, Mona Kandel, Mohammad A Alfhili, Abdulmajeed A Alabdullateef

Open access · diamondAbstract read
In one paragraph

Article in Saudi medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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  13. Assessment of the impact of pathogen reduction technologies on the neutralizing activity of COVID-19 convalescent plasma.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jawaher AlsughayyirFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Yasser AlmalkiFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Imtinan AlburaykFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Mohrah AlalshaikFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Ibrahim AljoniFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Mona KandelFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Mohammad A AlfhiliFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
Abdulmajeed A AlabdullateefFrom the Chair of Medical and Molecular Genetics Research (Alfhili), Department of Clinical Laboratory Sciences, and from the Department of Clinical Laboratory Sciences, (Alsughayyir, Alalshaik,), College of Applied Medical Sciences, King Saud University; from the Division of Hematology (Almalki), King Khalid University Hospital; from the Blood Transfusion Services Operation Centre (Aljoni, Kandel, Alabdullateef Ministry of Health, Riyadh; and from the Maternity and Children Hospital (Alburayk), Ministry of Health, Hail, Kingdom of Saudi Arabia.
King Khalid University Hospital · SAKing Saud University · SANational Blood Transfusion Service · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo establish a nationwide epidemiological profile of transfusion-transmittable infection (TTI) markers among seemingly healthy blood donors to update policies required to ensure blood safety.

methodsA nationwide, cross-sectional study was designed to examine donor demographics and TTI prevalence during 2020 using data provided by the Ministry of Health, Saudi Arabia.

resultsCollectively, a total of 375,218 whole blood units were donated, of which 32,758 (8.7%) were excluded due to TTI-related risk. The exclusion was based on a positive nucleic acid amplification test (NAT) or seroreactivity to hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), human T-cell lymphotropic virus (HTLV-I/II), syphilis, or malaria. Notably, the central (37.6%) and southern (33%) regions were the epicenters of TTI-reactive blood donors. Hepatitis B virus markers accounted for 85.7% and were the overall most prevalent of TTI-positive donations, followed by HCV at 5.9% and syphilis at 5.6%. In particular, anti-HBc and HBsAg were most prevalent in the south, while HBV NAT was highest in the center.

conclusionHepatitis B virus, HCV, and syphilis carry the greatest risk of TTI in Saudi Arabia. Including HBsAg screening is a necessary precautious measure to maintain blood safety.

Indexed as

Hepatitis BHepatitis CHIV InfectionsSyphilisTransfusion ReactionBlood DonorsCross-Sectional StudiesHepacivirusHepatitis B Surface AntigensHepatitis B virusHumansPrevalenceSaudi ArabiaHepatitis B Surface Antigensblood bankdemographichepatitisSaudi Arabiatransfusion-transmitted infection

Identifiers

PMID36517064
PMCPMC9994514
OpenAlexW4311668380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.