ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2024
Measurement of Turbulent Kinetic Energy in Hypertrophic Cardiomyopathy Using Triple-velocity Encoding 4D Flow MR Imaging.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 6 citations in OpenAlex.
- Unlocking the Hemodynamic Signature in Hypertrophic Cardiomyopathy: A Path to Better Risk Stratification.JACC. Asia · 2026Article
- Prognostic Value of Left Ventricular Kinetic Energy for Predicting Major Adverse Events in Hypertrophic Cardiomyopathy.JACC. Asia · 2026Article
- Cardiovascular Flow Imaging.Journal of the Korean Society of Radiology · 2026Review
- Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Long-Term Follow-Up of Deformations and Hemodynamics.Journal of magnetic resonance imaging : JMRI · 2026Article
- 4D Flow MRI Velocity and Turbulence Mapping in Mild Valvular Heart Disease.Journal of magnetic resonance imaging : JMRI · 2026Observational
- Quantitative Evaluation of Carotid Artery Stenosis by Multi-VENC 4D Flow MRI: Incorporating Turbulent Kinetic Energy for Clinical Validity.Journal of magnetic resonance imaging : JMRI · 2025Article
- 4D flow MRI enhances prototype testing of a total artificial heart.Scientific reports · 2025Article
- Evaluation of the presence and severity of spontaneous splenorenal or gastrorenal shunts via four-dimensional flow magnetic resonance imaging: a preliminary study.Quantitative imaging in medicine and surgery · 2024Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe turbulent kinetic energy (TKE) estimation based on 4D flow MRI has been currently developed and can be used to estimate the pressure gradient. The objective of this study was to validate the clinical value of 4D flow-based TKE measurement in patients with hypertrophic cardiomyopathy (HCM).
methodsFrom April 2018 to March 2019, we recruited 28 patients with HCM. Based on echocardiography, they were divided into obstructed HCM (HOCM) and non-obstructed HCM (HNCM). Triple-velocity encoding 4D flow MRI was performed. The volume-of-interest from the left ventricle to the aortic arch was drawn semi-automatically. We defined peak turbulent kinetic energy (TKE
resultsTKE
conclusionTKE measurement based on 4D flow MRI can detect the flow alteration induced by systolic flow jet and LV outflow tract geometry, such as SAM in patients with HOCM. The elevated TKE is correlated with increasing LV mass. This indicates that increasing cardiac load, by pressure loss due to turbulence, induces progression of LV hypertrophy, which leads to a worse prognosis.
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