Evidence map›Paper›PMID 36516973›Full record

ArticleBiomacromolecules2023

Synthesis, Characterization, and Digital Light Processing of a Hydrolytically Degradable Hyaluronic Acid Hydrogel.

Jonathan H Galarraga, Abhishek P Dhand, Bruce P Enzmann, Jason A Burdick

Open access · greenAbstract read
In one paragraph

Article in Biomacromolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Lithography-based 3D printing of hydrogels.Nature reviews bioengineering · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Programmable Tissue Folding Patterns in Structured Hydrogels.Advanced materials (Deerfield Beach, Fla.) · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Radical-Mediated Degradation of Thiol-Maleimide Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathan H GalarragaDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-1146-5941
Abhishek P DhandDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Bruce P EnzmannDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Jason A BurdickDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-2006-332X
University of Pennsylvania · USUniversity of Colorado Boulder · US

Funding

Engineered Granular Hydrogels for Endogenous Tissue RepairR01HL160616 · NHLBI · UNIVERSITY OF COLORADO · PI BURDICK, JASON A · 2022 to 2025
$2.5M
Engineered Developmental Microenvironments: Cartilage Formation and MaturationR01AR077362 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI BURDICK, JASON A, MAUCK, ROBERT L · 2020 to 2024
$2.5M
NHLBI NIH HHS R01 HL160616NIAMS NIH HHS R01 AR077362
6 · The paper itself

Abstract

Numerous chemical modifications of hyaluronic acid (HA) have been explored for the formation of degradable hydrogels that are suitable for a variety of biomedical applications, including biofabrication and drug delivery. Thiol-ene step-growth chemistry is of particular interest due to its lower oxygen sensitivity and ability to precisely tune mechanical properties. Here, we utilize an aqueous esterification route via reaction with carbic anhydride to synthesize norbornene-modified HA (NorHA

Indexed as

Hyaluronic AcidHydrogelsEstersPolyethylene GlycolsSulfhydryl CompoundsTissue EngineeringEstersHyaluronic AcidHydrogelsPolyethylene GlycolsSulfhydryl Compounds

Identifiers

PMID36516973
PMCPMC10928645
OpenAlexW4311582095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.