Evidence map›Paper›PMID 36516815›Full record

ArticleImmunity2022

Good intentions gone wrong: The B cell block to epithelial repair.

Emilie K Grasset, Theresa Alenghat

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Emilie K GrassetDepartment of Medicine, Division of Clinical Immunology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Drukier Institute for Children's Health and Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, Weill Cornell Medicine, Cornell University, New York, NY, USA.
Theresa AlenghatDivision of Immunobiology and Center for Inflammation and Tolerance, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: theresa.alenghat@cchmc.org.
Icahn School of Medicine at Mount Sinai · USUniversity of Cincinnati · US

Funding

Host integration of commensal and pathogenic bacterial-derived signalsR01DK116868 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Theresa Alenghat · 2018 to 2026
$4.1M
Epigenomic control of antimicrobial immunity in the intestineR01DK114123 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI ALENGHAT, THERESA · 2018 to 2022
$1.8M
NIDDK NIH HHS R01 DK114123NIDDK NIH HHS R01 DK116868
6 · The paper itself

Abstract

Cellular dynamics that influence mucosal healing are not well understood. In this issue of Immunity, Frede, Czarnewski, Monasterio et al. find that B cells accumulate in the colon following intestinal injury. These B cells impair epithelial repair by hindering local stromal-epithelial interactions.

Indexed as

IntentionIntestinal MucosaColonEpithelial Cells

Identifiers

PMID36516815
PMCPMC11008460
OpenAlexW4311309880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.