Evidence map›Paper›PMID 36516778›Full record

ArticleCell reports2022

Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages.

Jiaqing Hao, Rong Jin, Jun Zeng, Yuan Hua, Matthew S Yorek, Lianliang Liu, Anita Mandal, Junling Li, Huaiyu Zheng, Yanwen Sun and 9 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 2 countries.

Jiaqing HaoDepartment of Pathology, University of Iowa, 431 Newton Road, Iowa City, IA, USA; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Rong JinDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA; NHC Key Laboratory of Medical Immunology, Department of Immunology, School of Basic Medical Sciences, Peking University, Beijing, China.
Jun ZengDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA; School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Yuan HuaDepartment of Pathology, University of Iowa, 431 Newton Road, Iowa City, IA, USA; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Matthew S YorekDepartment of Pathology, University of Iowa, 431 Newton Road, Iowa City, IA, USA.
Lianliang LiuDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA; College of Food and Pharmaceutical Sciences, Ningbo University, Ningbo, China.
Anita MandalDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Junling LiDepartment of Radiology, University of Louisville, Louisville, KY, USA.
Huaiyu ZhengDepartment of Radiology, University of Louisville, Louisville, KY, USA.
Yanwen SunDepartment of Pathology, University of Iowa, 431 Newton Road, Iowa City, IA, USA; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Yanmei YiDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA; Department of Histology and Embryology, Guangdong Medical University, Zhanjiang, China.
Di YinDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA; School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Qi ZhengBioinformatics and Biostatistics, Department of Public Health, University of Louisville, Louisville, KY, USA.
Xiaohong LiKentucky Biomedical Research Infrastructure Network Bioinformatics Core, Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, USA.
Chin K NgDepartment of Radiology, University of Louisville, Louisville, KY, USA.
Eric C RouchkaKentucky Biomedical Research Infrastructure Network Bioinformatics Core, Department of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY, USA; Department of Computer Science and Engineering, University of Louisville, Louisville, KY, USA.
Nejat K EgilmezDepartment of Microbiology and Immunology, University of Louisville, Louisville, KY, USA.
Ali JabbariDepartment of Dermatology, University of Iowa, Iowa City, IA, USA; Iowa City VA Medical Center, Iowa City, IA, USA.
Bing LiDepartment of Pathology, University of Iowa, 431 Newton Road, Iowa City, IA, USA; Department of Microbiology and Immunology, University of Louisville, Louisville, KY, USA. Electronic address: bing-li@uiowa.edu.
University of Louisville · USUniversity of Iowa · USNingbo University · CN

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
The role of ECM-mediated mechanosignaling on regional immunosuppression in GBMP20GM135004 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Sharmila Nair · 2020 to 2026
$21.1M
Determine the role of SETDB1 in controlling lipid metabolism in obesity-associated cancerU01CA272424 · NCI · UNIVERSITY OF IOWA · PI Bing Li · 2022 to 2026
$6.0M
PILOT PROJECT PROGRAMP30GM106396 · NIGMS · UNIVERSITY OF LOUISVILLE · PI MILLER, DONALD M. · 2013 to 2017
$5.4M
Prevention of Breast Cancer Development by Epidermal Fatty Acid Binding Protein (R01CA180986 · NCI · UNIVERSITY OF MINNESOTA · PI LI, BING · 2014 to 2025
$3.3M
Immunomodulatory mechanisms of E-FABP in psoriasis pathogenesisR01AI137324 · NIAID · UNIVERSITY OF LOUISVILLE · PI LI, BING · 2018 to 2022
$1.9M
NCI NIH HHS R01 CA180986NCI NIH HHS U01 CA272424NIAID NIH HHS R01 AI137324NIGMS NIH HHS P20 GM103436NIGMS NIH HHS P20 GM135004NIGMS NIH HHS P30 GM106396
6 · The paper itself

Abstract

Fats are essential in healthy diets, but how dietary fats affect immune cell function and overall health is not well understood. Mimicking human high-fat diets (HFDs), which are rich in different fatty acid (FA) components, we fed mice various HFDs from different fat sources, including fish oil and cocoa butter. Mice consuming the fish oil HFD exhibit a hair-loss phenotype. Further studies show that omega-3 (n-3) FAs in fish oil promote atypical infiltration of CD207

Indexed as

Fatty Acids, Omega-3Fish OilsAlopeciaAnimalsDietary FatsDiet, High-FatFatty Acid-Binding ProteinsHumansMacrophagesMiceTumor Necrosis Factor-alphaDietary FatsFatty Acid-Binding ProteinsFatty Acids, Omega-3Fish OilsTumor Necrosis Factor-alphaCP: ImmunologyCP: Metabolismfatty acid binding proteinfish oilhair losshigh-fat dietmacrophages

Identifiers

PMID36516778
PMCPMC10193786
OpenAlexW4311310345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.