Evidence map›Paper›PMID 36516561›Full record

ArticleClinical biomechanics (Bristol, Avon)2023

Robot and ultrasound assisted needle insertion to the transverse carpal ligament.

Jocelyn L Hawk, Hui Zhang, David S Margolis, Zong-Ming Li

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 72% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jocelyn L HawkHand Research Laboratory, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Arizona, AZ, USA.
Hui ZhangHand Research Laboratory, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Arizona, AZ, USA.
David S MargolisHand Research Laboratory, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Arizona, AZ, USA.
Zong-Ming LiHand Research Laboratory, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Arizona, AZ, USA. Electronic address: lizongming@arizona.edu.
University of Arizona · US

Funding

Collagenolysis of the transverse carpal ligamentR21AR075402 · NIAMS · UNIVERSITY OF ARIZONA · PI LI, ZONG-MING · 2020 to 2021
$365k
NIAMS NIH HHS R21 AR075402
6 · The paper itself

Abstract

backgroundA potential alternative treatment to surgery for carpal tunnel syndrome is to inject enzymes into the transverse carpal ligament to decrease its stiffness and alleviate pressure off the median nerve. An accurate injection is needed for delivery to achieve the effects of tissue degradation. The purposes of this study were to 1) determine injection sites using 3D reconstructed anatomy, and 2) insert the needle to the middle of the transverse carpal ligament thickness in situ.

methodsSix fresh-frozen cadaveric hands were used in this study. Five injection sites were determined in the sagittal plane along the center of the transverse carpal ligament thickness ulnar to the thenar muscle attachment using 3D ultrasonographic reconstruction. Each injection was delivered by rigidly fixing a 27-gauge needle to a six degrees of freedom robot arm programmed to insert the needle tip to the intended target. Ultrasound images were taken of the needle after insertion to measure accuracy and precision of the needle placement.

findingsThe needle tip was successfully delivered to the middle region of the transverse carpal ligament thickness and visualized using ultrasound imaging. The accuracy and precision of the needle insertion were 0.83 and 0.31 mm, respectively.

interpretationMethodology was established for robot-assisted needle insertion to the transverse carpal ligament using 3D ultrasonographic reconstructed anatomy. This methodology can be used in the future to deliver enzymatic injections to the transverse carpal ligament as a potential treatment for carpal tunnel syndrome.

Indexed as

Carpal Tunnel SyndromeRoboticsHumansLigaments, ArticularMedian NerveUltrasonographyWrist Joint3D reconstructionCarpal tunnel syndromeInjectionRobotUltrasound imaging

Identifiers

PMID36516561
PMCPMC9892213
OpenAlexW4310817824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.