Evidence map›Paper›PMID 36515933›Full record

ArticleTexas Heart Institute journal2022

Improved Physical Function After Cardiac Contractility Modulation Therapy in 10 Patients With Chronic Heart Failure.

Karine Vartanian, Miguel Franco, Nathalie Busse, Sofiia Bidzhoian, Tesnim Hamdan, Ernst R von Schwarz

Open access · diamondAbstract read
In one paragraph

Article in Texas Heart Institute journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karine VartanianSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Miguel FrancoSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Nathalie BusseSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Sofiia BidzhoianSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Tesnim HamdanSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Ernst R von SchwarzSouthern California Hospital Heart Institute, Southern California Hospital at Culver City, Culver City, California.
Cedars-Sinai Smidt Heart Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA new generation of therapeutic devices has expanded the options for managing advanced heart failure. We examined the outcomes of cardiac contractility therapy in a series of 10 patients with chronic heart failure.

methodsTen patients with chronic heart failure were nonrandomly selected to receive cardiac contractility modulation therapy. Hemodynamics, left ventricular ejection fraction, functional capacity, and clinical outcomes were evaluated at baseline and after 6 months of therapy.

resultsEight male and 2 female patients (mean [SD] age, 63.4 [9.4] years) received cardiac contractility modulation therapy. Between baseline and 6-month follow-up, mean (SD) left ventricular ejection fraction improved from 27.1% (4.18%) to 35.1% (9.89%), New York Heart Association class declined from 3.9 (0.32) to 2.44 (0.52), and 6-minute walk test distance increased from 159.2 (93.79) m to 212.4 (87.24) m. Furthermore, the mean (SD) number of hospital admissions within the 6 months before cardiac contractility modulation therapy was 2.4 (2.27) compared with 1 (1.52) during the 6 months after therapy.

conclusionCardiac contractility modulation therapy improved physical functioning and reduced hospital admissions in these patients.

Indexed as

Heart FailureVentricular Function, LeftChronic DiseaseFemaleHumansMaleMiddle AgedMyocardial ContractionStroke VolumeTreatment Outcomeheart failureMyocardial contractionwalk test, 6-minute

Identifiers

PMID36515933
PMCPMC9809076
OpenAlexW4311478771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.