Evidence map›Paper›PMID 36515810›Full record

ReviewMagma (New York, N.Y.)2023

Quantitative MRI of diffuse liver diseases: techniques and tissue-mimicking phantoms.

Aaryani Tipirneni-Sajja, Sarah Brasher, Utsav Shrestha, Hayden Johnson, Cara Morin, Sanjaya K Satapathy

Open access · greenAbstract readReview
In one paragraph

Review in Magma (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Aaryani Tipirneni-SajjaDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN, USA. aaryani.sajja@memphis.edu.ORCID http://orcid.org/0000-0002-3246-8711
Sarah BrasherDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN, USA.
Utsav ShresthaDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN, USA.
Hayden JohnsonDepartment of Biomedical Engineering, The University of Memphis, Memphis, TN, USA.
Cara MorinDepartment of Diagnostic Imaging, St. Jude Children's Research Hospital, Memphis, TN, USA.
Sanjaya K SatapathyNorthwell Health Center for Liver Diseases and Transplantation, Northshore University Hospital/Northwell Health, Manhasset, NY, USA.
University of Memphis · USCincinnati Children's Hospital Medical Center · USNorthwell Health · USSt. Jude Children's Research Hospital · US

Funding

MODELING MRI-BASED TISSUE RELAXATION IN THE PRESENCE OF IRON OVERLOAD AND STEATOSISR21EB031298 · NIBIB · UNIVERSITY OF MEMPHIS · PI TIPIRNENI-SAJJA, AARYANI · 2021 to 2022
$589k
NIBIB NIH HHS R21 EB031298NIBIB NIH HHS R21EB031298
6 · The paper itself

Abstract

Quantitative magnetic resonance imaging (MRI) techniques are emerging as non-invasive alternatives to biopsy for assessment of diffuse liver diseases of iron overload, steatosis and fibrosis. For testing and validating the accuracy of these techniques, phantoms are often used as stand-ins to human tissue to mimic diffuse liver pathologies. However, currently, there is no standardization in the preparation of MRI-based liver phantoms for mimicking iron overload, steatosis, fibrosis or a combination of these pathologies as various sizes and types of materials are used to mimic the same liver disease. Liver phantoms that mimic specific MR features of diffuse liver diseases observed in vivo are important for testing and calibrating new MRI techniques and for evaluating signal models to accurately quantify these features. In this study, we review the liver morphology associated with these diffuse diseases, discuss the quantitative MR techniques for assessing these liver pathologies, and comprehensively examine published liver phantom studies and discuss their benefits and limitations.

Indexed as

Fatty LiverIron OverloadLiver DiseasesFibrosisHumansLiverMagnetic Resonance ImagingPhantoms, ImagingDWIElastographyFat fractionFibrosisIron overloadLiverMRIPhantomsR2*SteatosisT1

Identifiers

PMID36515810
PMCPMC12145508
OpenAlexW4311392680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.