Evidence map›Paper›PMID 36515527›Full record

ArticleMicrobiology spectrum2023

Clinical Outcomes and Risk Factors for Death following Carbapenem-Resistant Klebsiella pneumoniae Infection in Solid Organ Transplant Recipients.

Jingli Lu, Ailing Zhang, Lu Han, Zhen Guo, Wenjing Cui, Yuhua Jiang, Haiyang Meng

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Burden and Management of Multi-Drug Resistant Organism Infections in Solid Organ Transplant Recipients Across the World: A Narrative Review.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jingli LuDepartment of Pharmacy, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-7411-1430
Ailing ZhangDepartment of Pharmacy, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lu HanSecond People's Hospital of Zhengzhou, Zhengzhou, China.
Zhen GuoFirst People's Hospital of Xiangcheng, Xiangcheng, China.
Wenjing CuiXiangcheng Hospital of Chinese Medicine, Xiangcheng, China.
Yuhua JiangAffiliated Hospital of Huanghe Science and Technology University, Zhengzhou, China.
Haiyang MengDepartment of Pharmacy, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhengzhou University · CNHuanghe Science and Technology College · CNXiangyang Hospital of Traditional Chinese Medicine · CNXian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP) are associated with significant morbidity and mortality. Among solid organ transplant recipients (SOTRs), clinical outcomes and risk factors for death following such infections remain not well documented. A single-center retrospective study was performed. All SOTRs with a CRKP infection at the First Affiliated Hospital of Zhengzhou University between 1 January 2018 and 31 December 2021 were included. Multivariable Cox regression was performed to determine risk factors for death following CRKP infection. We identified 94 SOTRs with CRKP infection, with a median age of 50 years old. CRKP infections resulted in 38.3% of overall 30-day mortality. On multivariable analysis, independent risk factors for death following CRKP infection included older age (hazard ratio [HR], 1.044; 95% confidence interval [CI], 1.007 to 1.083;

Indexed as

Klebsiella InfectionsOrgan TransplantationShock, SepticAnti-Bacterial AgentsCarbapenemsDrug Resistance, BacterialHumansKlebsiella pneumoniaeMiddle AgedRetrospective StudiesRisk FactorsAnti-Bacterial AgentsCarbapenemsallograft failureappropriate targeted therapycarbapenem-resistant Klebsiella pneumoniaeorgan transplantseptic shock

Identifiers

PMID36515527
PMCPMC9927413
OpenAlexW4311489381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.